Evidence map›Paper›PMID 39000160›Full record

ArticleInternational journal of molecular sciences2024

Far-Ultraviolet Light at 222 nm Affects Membrane Integrity in Monolayered DLD1 Colon Cancer Cells.

Jun Nishikawa, Yuta Tamura, Tomohiro Fujii, Soichiro Fukuda, Shoma Yoneda, Nanami Yamaura, Shinichi Takahashi, Takeshi Yamamoto, Junzo Nojima, Yutaka Suehiro and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jun NishikawaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.ORCID 0000-0002-6695-9754
Yuta TamuraFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Tomohiro FujiiFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Soichiro FukudaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Shoma YonedaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Nanami YamauraFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Shinichi TakahashiFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Takeshi YamamotoFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Junzo NojimaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Yutaka SuehiroDepartment of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Takahiro YamasakiDepartment of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.ORCID 0000-0002-9793-0399
Taro TakamiDepartment of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.ORCID 0000-0002-6689-4989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

222 nm far-ultraviolet (F-UV) light has a bactericidal effect similar to deep-ultraviolet (D-UV) light of about a 260 nm wavelength. The cytotoxic effect of 222 nm F-UV has not been fully investigated. DLD-1 cells were cultured in a monolayer and irradiated with 222 nm F-UV or 254 nm D-UV. The cytotoxicity of the two different wavelengths of UV light was compared. Changes in cell morphology after F-UV irradiation were observed by time-lapse imaging. Differences in the staining images of DNA-binding agents Syto9 and propidium iodide (PI) and the amount of cyclobutane pyrimidine dimer (CPD) were examined after UV irradiation. F-UV was cytotoxic to the monolayer culture of DLD-1 cells in a radiant energy-dependent manner. When radiant energy was set to 30 mJ/cm

Indexed as

ApoptosisCell MembraneColonic NeoplasmsDNA DamageUltraviolet RaysCell Line, TumorHumansPyrimidine DimersPyrimidine Dimers222 nmcell deathfar-ultravioletmembrane damagemonolayer cells

Identifiers

PMID39000160
PMCPMC11241724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.