Evidence map›Paper›PMID 38999830›Full record

Trial reportNutrients2024

Beneficial Effects of Synbiotics on the Gut Microbiome in Individuals with Low Fiber Intake: Secondary Analysis of a Double-Blind, Randomized Controlled Trial.

Aakash Mantri, Linda Klümpen, Waldemar Seel, Peter Krawitz, Peter Stehle, Bernd Weber, Leonie Koban, Hilke Plassmann, Marie-Christine Simon

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The gut microbiota in malnutrition.Nature reviews. Microbiology · 2026
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aakash MantriInstitute of Nutrition and Food Science, Nutrition and Microbiota, University of Bonn, 53115 Bonn, Germany.ORCID 0000-0001-6763-5674
Linda KlümpenInstitute of Nutrition and Food Science, Nutrition and Microbiota, University of Bonn, 53115 Bonn, Germany.ORCID 0009-0007-2045-4412
Waldemar SeelInstitute of Nutrition and Food Science, Nutrition and Microbiota, University of Bonn, 53115 Bonn, Germany.ORCID 0009-0004-4443-9143
Peter KrawitzInstitute for Genomic Statistics and Bioinformatics, University Hospital Bonn, 53127 Bonn, Germany.
Peter StehleInstitute of Nutrition and Food Science, Nutritional Physiology, University of Bonn, 53115 Bonn, Germany.ORCID 0000-0002-4596-8088
Bernd WeberInstitute of Experimental Epileptology and Cognition Research, University of Bonn, 53115 Bonn, Germany.
Leonie KobanLyon Neuroscience Research Center (CRNL), Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Université Claude Bernard Lyon 1, 69500 Lyon, France.
Hilke PlassmannLyon Neuroscience Research Center (CRNL), Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Université Claude Bernard Lyon 1, 69500 Lyon, France.ORCID 0000-0001-9680-0763
Marie-Christine SimonInstitute of Nutrition and Food Science, Nutrition and Microbiota, University of Bonn, 53115 Bonn, Germany.ORCID 0000-0001-6625-1265

Funding

Bundesministerium für Bildung und Forschung 01EA1707
6 · The paper itself

Abstract

Insufficient dietary fiber intake can negatively affect the intestinal microbiome and, over time, may result in gut dysbiosis, thus potentially harming overall health. This randomized controlled trial aimed to improve the gut microbiome of individuals with low dietary fiber intake (<25 g/day) during a 7-week synbiotic intervention. The metabolically healthy male participants (

Indexed as

Dietary FiberFecesGastrointestinal MicrobiomeSynbioticsAdultDouble-Blind MethodHumansMaleYoung AdultDietary Fiberdysbiosisfibergut microbiotaintervention studyprebioticprobioticsynbiotics

Identifiers

PMID38999830
PMCPMC11243043

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.