Evidence map›Paper›PMID 38999331›Full record

ArticleJournal of clinical medicine2024

Centhaquine Increases Stroke Volume and Cardiac Output in Patients with Hypovolemic Shock.

Aman Khanna, Krish Vaidya, Dharmesh Shah, Amaresh K Ranjan, Anil Gulati

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05251181 (A Multi-Centric, Randomized, Double-Blind, Placebo-controlled, Phase-III Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent to be Used as an Adjuvant to Standard Treatment of Hypovolemic Shock), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05251181 phase3not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Multi-Centric, Randomized, Double-Blind, Placebo-controlled, Phase-III Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent to be Used as an Adjuvant to Standard Treatment of Hypovolemic Shock

TypeinterventionalSponsorPharmazz, Inc.Ran2026 to 2027Enrolled430ConditionsHypovolemic ShockArmsNormal Saline, Centhaquine
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aman KhannaAman Hospital and Research Centre Organization, Vadodara 390021, GJ, India.
Krish VaidyaI Cure Heart Care, Vadodara 390007, GJ, India.
Dharmesh ShahPharmazz India Private Limited, Greater Noida 201307, UP, India.ORCID 0009-0004-3431-972X
Amaresh K RanjanPharmazz Inc., Research and Development, Willowbrook, IL 60527, USA.
Anil GulatiPharmazz Inc., Research and Development, Willowbrook, IL 60527, USA.ORCID 0000-0002-7420-4554

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood pressurecardiac outputcenthaquinecritical carehypovolemiaresuscitationshockvenous return

Identifiers

PMID38999331
PMCPMC11242165

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.