Evidence map›Paper›PMID 38998936›Full record

ArticleMolecules (Basel, Switzerland)2024

Uncovering Metabolic Alterations in HCT-116 Colon Cancer Cells upon Exposure to Bamboo Leaf Extract Obtained from

Luis Carlos Chitiva, Mary Andrea Santamaría-Torres, Paula Rezende-Teixeira, Jessica Rodrigues Pereira de Oliveira Borlot, Rodrigo de Almeida Romagna, Ximena Londoño, Rodrigo Rezende Kitagawa, Leticia V Costa-Lotufo, Juliet A Prieto-Rodríguez, Ian Castro-Gamboa and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Metabolomic Profiling ofACS omega · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luis Carlos ChitivaGrupo de Investigación Fitoquímica Universidad Javeriana (GIFUJ), Department of Chemistry, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0003-1422-5545
Mary Andrea Santamaría-TorresUniversidad de los Andes, Bogotá 111711, Colombia.
Paula Rezende-TeixeiraLaboratório de Farmacologia de Produtos Naturais Marinhos, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Jessica Rodrigues Pereira de Oliveira BorlotLaboratório de Triagem Biológica de Produtos Naturais, Department of Pharmaceutical Sciences, Federal University of Espírito Santo (UFES), Vitoria 29047-105, Brazil.
Rodrigo de Almeida RomagnaLaboratório de Triagem Biológica de Produtos Naturais, Department of Pharmaceutical Sciences, Federal University of Espírito Santo (UFES), Vitoria 29047-105, Brazil.ORCID 0009-0004-9294-7871
Ximena LondoñoFaculty of Agricultural Sciences, Universidad Nacional de Colombia, Palmira 763533, Colombia.ORCID 0000-0002-1577-1356
Rodrigo Rezende KitagawaLaboratório de Triagem Biológica de Produtos Naturais, Department of Pharmaceutical Sciences, Federal University of Espírito Santo (UFES), Vitoria 29047-105, Brazil.
Leticia V Costa-LotufoLaboratório de Farmacologia de Produtos Naturais Marinhos, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0003-1861-5153
Juliet A Prieto-RodríguezGrupo de Investigación Fitoquímica Universidad Javeriana (GIFUJ), Department of Chemistry, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0002-7064-2389
Ian Castro-GamboaNúcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais (NuBBE), Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-900, Brazil.ORCID 0000-0002-2353-0181
Geison Modesti CostaGrupo de Investigación Fitoquímica Universidad Javeriana (GIFUJ), Department of Chemistry, Faculty of Sciences, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0003-2449-1986

Funding

National Council for Scientific and Technological Development 23038.000776/2017-54Pontificia Universidad Javeriana 20834Pontificia Universidad Javeriana, Ministerio de Ciencia, Tecnología e Innovación, Ministerio de Educación Nacional, Ministerio de Industria, Comercio y Turismo e ICETEX, 2ª Convocatoria Ecosistema Científico - Colombia Científica 792-2017 FP44842-221-2018
6 · The paper itself

Abstract

Metabolic alterations are increasingly recognized as important aspects of colorectal cancer (CRC), offering potential avenues for identifying therapeutic targets. Previous studies have demonstrated the cytotoxic potential of bamboo leaf extract obtained from

Indexed as

Colonic NeoplasmsPlant ExtractsPlant LeavesAnimalsApoptosisCell SurvivalChromatography, LiquidHCT116 CellsHumansMetabolomeMetabolomicsMiceRAW 264.7 CellsPlant Extractsanti-inflammatory activitybamboo leaf extractcytotoxic activityendometabolomeexometabolomeGuadua incanaHCT-116 cellsmetabolomics

Identifiers

PMID38998936
PMCPMC11243423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.