Evidence map›Paper›PMID 38998931›Full record

ArticleMolecules (Basel, Switzerland)2024

Preparation of Pinoresinol and Dehydrodiconiferyl Alcohol from Eucommiae Cortex Extract by Fermentation with Traditional Mucor.

Wenyi Jiang, Zhengyou He, Ruijiao Yao, Zhiyang Chen, Xia Zeng, Miao Zheng, Jing Wang, Jia Li, Yong Jiang

Erratum issuedAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Comparison of Anti-Renal Fibrosis Activity ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Wenyi JiangSchool of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Zhengyou HeSchool of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Ruijiao YaoSchool of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Zhiyang ChenSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.
Xia ZengSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.
Miao ZhengSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.
Jing WangSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.
Jia LiSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.
Yong JiangSchool of Pharmacy, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eucommiae Cortex (EC) is frequently used alone or in combination with other active ingredients to treat a range of illnesses. An efficient technical instrument for changing cheap or plentiful organic chemicals into rare or costly counterparts is biotransformation. It combines EC with biotransformation techniques with the aim of producing some novel active ingredients, using different strains of bacteria that were introduced to biotransform EC in an aseptic environment. The high-quality strains were screened for identification after the fermentation broth was found using HPLC, and the primary unidentified chemicals were separated and purified in order to be structurally identified. Strain 1 was identified as Aspergillus niger and strain 2 as Actinomucor elegans; the main transformation product A was identified as dehydrodiconiferyl alcohol (DA) and B as pinoresinol (Pin). The biotransformation of EC utilizing Aspergillus niger and Actinomucor elegans is reported for the first time in this study’s conclusion, resulting in the production of Pin and DA.

Indexed as

Aspergillus nigerBiotransformationEucommiaceaeFermentationLignansMucorPlant ExtractsChromatography, High Pressure LiquidFuransFuransLignanspinoresinolPlant ExtractsActinomucor elegansAspergillus nigerbiotransformationdehydrodiconiferyl alcoholEucommiae Cortexpinoresinol

Identifiers

PMID38998931
PMCPMC11243097

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.