Evidence map›Paper›PMID 38997861›Full record

ArticleSurgery2024

Which individual components of a colorectal surgery enhanced recovery program are associated with improved surgical outcomes?

Bayley A Jones, Bethany Brock, Joshua Richman, Lauren Wood, Alfonsus Adrian H Harsono, Wendelyn M Oslock, Nathan C English, Michael Rubyan, Daniel I Chu

Abstract read
In one paragraph

Article in Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Bayley A JonesDepartment of Surgery, University of Alabama at Birmingham, AL. Electronic address: https://twitter.com/bayley_jones.
Bethany BrockDepartment of Surgery, University of Alabama at Birmingham, AL.
Joshua RichmanDepartment of Surgery, University of Alabama at Birmingham, AL.
Lauren WoodDepartment of Surgery, University of Alabama at Birmingham, AL.
Alfonsus Adrian H HarsonoDepartment of Surgery, University of Alabama at Birmingham, AL; Department of Obstetrics and Gynecology, University of Alabama at Birmingham, AL.
Wendelyn M OslockDepartment of Surgery, University of Alabama at Birmingham, AL; Department of Quality, Birmingham Veterans Affairs Medical Center, AL.
Nathan C EnglishDepartment of Surgery, University of Cape Town, South Africa.
Michael RubyanSchool of Public Health, University of Michigan, Ann Arbor, MI.
Daniel I ChuDepartment of Surgery, University of Alabama at Birmingham, AL. Electronic address: dchu@uabmc.edu.

Funding

Designing a Plan of Action for Better Access and Quality of Surgery for African-Americans with Gastrointestinal Cancers in the Deep SouthR01MD013858 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHU, DANIEL I, PISU, MARIA · 2020 to 2024
$3.0M
Adapting Enhanced Recovery Programs (ERPs) through Health Literacy to Eliminate Surgical DisparitiesR01CA271303 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Daniel I Chu · 2023 to 2026
$2.1M
Enhancing Health Literacy in Surgery (EHLIS) to Eliminate Surgical Disparities for African-Americans with Inflammatory Bowel Disease (IBD)K23MD013903 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHU, DANIEL I · 2019 to 2021
$434k
Short-Term Research Experiences Advancing Medical Students (STREAMS)T35DK116670 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HERBERT CHEN, Daniel I Chu · 2019 to 2026
$371k
AHRQ HHS K12 HS023009NCI NIH HHS R01 CA271303NIDDK NIH HHS T35 DK116670NIMHD NIH HHS K23 MD013903NIMHD NIH HHS R01 MD013858
6 · The paper itself

Abstract

backgroundEnhanced recovery programs improve surgical outcomes. However, the association of adherence to individual components and outcomes in a comprehensive enhanced recovery program remains unclear.

methodsWe performed a retrospective study of all elective colorectal surgery patients at our institution from 2019 to 2022 (n = 1,175). Data were acquired from our institution's enhanced recovery program dashboard and American College of Surgeons National Surgical Quality Improvement Program database. Traditional analyses and machine-learning classification trees were used to identify enhanced recovery program components associated with length of stay, readmissions, and complication rates.

resultsThe average length of stay was 5.0 days, readmission rate was 12.3%, and complication rate was 32.6%. On linear regression analysis, adherence to preoperative education, regional analgesia, pre- and postoperative multimodal analgesia, no nasogastric tube, early mobilization, early regular diet, early discontinuation of maintenance intravenous fluids, postoperative venous thromboembolism prophylaxis, and early Foley catheter removal were associated with an decrease in length of stay by 0.7-7.1 days (P < .05). Patients who adhered to no prolonged fasting had a 4.1% decrease in readmission rate (P = .04). Patients who adhered to no nasogastric tube, early mobilization, early regular diet, postoperative multimodal analgesia, and discontinuation of maintenance intravenous fluids had decreases in complication rates ranging from 7.0 to 28.2% (P < .001). Machine learning demonstrated that no nasogastric tube and discontinuation of maintenance intravenous fluids were significant predictors of shorter length of stay and no nasogastric tube and early mobilization were significant predictors of reduced complication rates.

conclusionsAlthough multiple components were associated outcomes, no nasogastric tube, early mobilization, early regular diet, postoperative multimodal analgesia, and early discontinuation of maintenance intravenous fluids were associated with more than 1 outcome. Focusing on these components may make enhanced recovery program implementation more feasible for resource-limited hospitals.

Indexed as

Enhanced Recovery After SurgeryLength of StayPatient ReadmissionAgedColorectal SurgeryElective Surgical ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsQuality ImprovementRetrospective StudiesTreatment Outcome

Identifiers

PMID38997861
PMCPMC11381166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.