Evidence map›Paper›PMID 38997778›Full record

ArticleBMC sports science, medicine & rehabilitation2024

Cardiac rehabilitation in children and adolescents with long QT syndrome: the RYTHMO'FIT pilot study.

Luc Souilla, Sophie Guillaumont, Annie Auer, Gael Metzler, Anne Requirand, Marie Vincenti, Gregoire De La Villeon, Jean-Luc Pasquie, Denis Mottet, Pascal Amedro

2 registry-linked trialsAbstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04712136 nacompletednot on this map

Healthy-related Quality of Life and Physical Activity of Children With Inherited Cardiac Arrhythmia or Inherited Cardiomyopathies: the Prospective Multicentre Controlled QUALIMYORYTHM Study

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2021 to 2023Enrolled214ConditionsLong QT Syndrome, Brugada Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Arrhythmogenic Right Ventricular DysplasiaArmsMRI
NCT05964322 completednot on this map

Cardiac Rehabilitation of Children and Adolescent With Long QT Syndrome

TypeobservationalSponsorUniversity Hospital, MontpellierRan2022 to 2024Enrolled8ConditionsLong QT Syndrome, Congenital Long Qt Syndrome, Inherited Cardiac Conduction Disorder, Pediatric ALL
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luc SouillaPhyMedExp, CNRS, INSERM, University of Montpellier, Montpellier, France.
Sophie GuillaumontCHRU Montpellier, Department of Pediatric and Congenital Cardiology, M3C Regional Reference Centre, Montpellier, France.
Annie AuerPediatric Cardiology and Rehabilitation Unit, Saint-Pierre Institute, Palavas-Les-Flots, France.
Gael MetzlerPediatric Cardiology and Rehabilitation Unit, Saint-Pierre Institute, Palavas-Les-Flots, France.
Anne RequirandDepartment of Physiology, CHU de Montpellier, Montpellier, France.
Marie VincentiPhyMedExp, CNRS, INSERM, University of Montpellier, Montpellier, France.
Gregoire De La VilleonCHRU Montpellier, Department of Pediatric and Congenital Cardiology, M3C Regional Reference Centre, Montpellier, France.
Jean-Luc PasquiePhyMedExp, CNRS, INSERM, University of Montpellier, Montpellier, France.
Denis MottetEuroMov Digital Health in Motion, IMT Mines Ales, University of Montpellier, Montpellier, France.
Pascal AmedroDepartment of Pediatric and Adult Congenital Cardiology, M3C National Reference Centre, Bordeaux University Hospital, Pessac, France. pascal.amedro@gmail.com.ORCID http://orcid.org/0000-0003-3649-0294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the feasibility, acceptability, safety, and short-term benefits of a tailored cardiac rehabilitation program for children and adolescents with long QT syndrome (LQTS).

methodsEight participants, aged between 6 and 18, with a positive LQTS genotype and impaired cardiorespiratory fitness, were enrolled in a 12-week centre-based cardiac rehabilitation program. The program included supervised exercise training group sessions (aerobic, resistance, and outdoor activities) and patient education workshops. Feasibility, acceptability, and safety of the program were prospectively monitored. Feedback from the parents, children, and professionals involved was collected from qualitative interviews. Short-term effects on cardiorespiratory fitness, muscle fitness, physical activity, and health-related quality of life (HRQoL) were measured between baseline and the end of the program.

resultsRetention (88% with one participant dropping out) and adherence (79%) rates were good, and no cardiac events occurred during the 12-week intervention period. Participants, parents, and healthcare professionals expressed a high level of satisfaction with the program. A significant increase between the beginning and the end of the program was observed for ventilatory anaerobic threshold (21.7±5.2 vs. 28.7±5.1 mL/kg/min, P=0.01, effect size=0.89), grip strength, (18±5.3 Kg vs. 20±4.7 Kg, P=0.02, effect size=0.90), lower limb explosive strength (142±36.5 cm vs. 148±24 cm, P=0.02, effect size=0.90), and parent-reported physical health dimension of HRQoL (65.6±9.75 vs. 84.4±20.35, P=0.03, effect size=0.87).

conclusionsA 12-week tailored centre-based cardiac rehabilitation program was feasible, acceptable, and safe for children with LQTS. Cardiac rehabilitation for children with LQTS presents a new approach aligned with secondary prevention in youth with cardiac diseases.

trial registrationThe trial was registered at Clinicaltrials.gov (NCT05964322, registration date: 27/07/2023).

Indexed as

Educational early interventionExerciseGenetic cardiac conditionsPatient-centered careYouth

Identifiers

PMID38997778
PMCPMC11245799

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.