Evidence map›Paper›PMID 38997763›Full record

ReviewChinese medicine2024

Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances.

Cheng Zhang, Anyang Rao, Cui Chen, Yuqing Li, Xiuchi Tan, Jiaxin Long, Xinyue Wang, Junjie Cai, Jiquan Huang, Hua Luo and 2 more

Abstract readReview
In one paragraph

Review in Chinese medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Discovery of 10-Shogaol fromJournal of agricultural and food chemistry · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Carbon dots derived fromFrontiers in molecular biosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cheng Zhang *Department of Pharmacy, Chengdu University of Traditional Chinese, Medicine, Chengdu, 611137, China.
Anyang Rao *Hongxing Town Government of Ruoergai County, Aba Tibetan and Qiang Autonomous Prefecture, Sichuan, 624504, China.
Cui Chen *The Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Yuqing LiThe Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Xiuchi TanDepartment of Pharmacy, Chengdu University of Traditional Chinese, Medicine, Chengdu, 611137, China.
Jiaxin LongDepartment of Pharmacy, Chengdu University of Traditional Chinese, Medicine, Chengdu, 611137, China.
Xinyue WangDepartment of Pharmacy, Chengdu University of Traditional Chinese, Medicine, Chengdu, 611137, China.
Junjie CaiThe Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Jiquan HuangThe Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.
Hua LuoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, 999078, China. hualuo@um.edu.mo.
Chuwen LiThe Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China. lichuwen@gzhmu.edu.cn.
Yuanye DangThe Fifth Affiliated Hospital, Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology & NMPA & State Key Laboratory, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China. dangyuanye@163.com.ORCID http://orcid.org/0000-0001-5685-6842

Funding

Administration of Traditional Chinese Medicine of Guangdong Province 20241183Chengdu University of Traditional Chinese Medicine MPRC2023033Disciplinary construction project of Guangzhou Medical University 02-445-2301221XMEducational Commission of Guangdong Province, China 2019KQNCX118Opening Project of Guangdong Province & NMPA & State Key Laboratory J24413003Plan on enhancing scientific research in Guangzhou Medical University 02-410-2302374XMPlan on enhancing scientific research in Guangzhou Medical University 02-410-2405012
6 · The paper itself

Abstract

All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and medicinal applications. Fresh ginger possesses the ability to effectively stimulate movement within the body, alleviate the act of vomiting, induce sweating, and provide relief for external syndromes. Dried ginger possesses both defensive and stimulant characteristics, which effectively raise the internal temperature and enhance the Yang energy. Fresh ginger is more hydrating than dried ginger, highly skilled at heating the Middle-jiao, alleviating pain, halting bleeding, and managing diarrhea. Dried ginger possesses the ability to alleviate coldness when consumed in a heated form, as well as to alleviate diarrhea when consumed in a heated form. It thrives in warm conditions and has a tendency to revert back to its warm nature. The moisture content of baked ginger is inferior to that of dried ginger, but it is highly effective in alleviating pain, bleeding, and diarrhea by warming the Middle-jiao. Ginger charcoal and stir-fried charcoal, produced through carbonization, have excellent heat retention properties and are effective in warming meridians and stopping bleeding. The potency and ability to spread of roasted ginger is less intense compared to fresh ginger, and its moisture content is not as low as that of dried ginger. The medicinal characteristics of this substance are gentle, making it beneficial for alleviating vomiting in patients who are physically frail. Its primary mode of action is on the Middle-jiao. Nevertheless, the main chemical compositions of various traditional Chinese medicines are nearly identical due to their shared base element. Ginger, in particular, possesses a range of pharmacological activities including antioxidant, anti-inflammatory, anti-tumor, anti-bacterial, and anticoagulant properties. However, modern pharmacological research has not fully acknowledged the clinical medicinal value of ginger and consequently, fails to provide accurate guidance for clinical medication. This situation has a negative impact on the contemporary advancement of traditional Chinese medicine (TCM). The research on modernizing ginger is conducted by analyzing and considering the prospects. It is based on Traditional Chinese Medicine (TCM) theory and incorporates the comprehensive perspective of TCM philosophy. In order to modernize ginger, it is essential to have a proper knowledge of the concepts of "recognizing nature by efficacy, homology, and mutual expression of nature and efficacy" and "rationally utilizing modern drug research technology". By applying these principles, we can construct a bridge towards the advancement of ginger.

Indexed as

Clinical applicationGingerOne source and multiple substancesPerformance and efficacyPharmacological activity

Identifiers

PMID38997763
PMCPMC11241951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.