Evidence map›Paper›PMID 38997735›Full record

SynthesisJournal of orthopaedic surgery and research2024

Efficacy comparison between intramedullary nail fixation and plate fixation in distal tibia fractures: a meta-analysis of randomized controlled trials.

Xiaobin Li, Kaipeng Chen, Haipeng Xue, Junwen Cheng, Xiaoping Yu

Abstract readMeta-AnalysisComparative StudySystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Intramedullary nailing versus plate fixation for the treatment of proximal tibia extra-articular fractures: a meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Pooled it
  3. Article
  4. Article
  5. Article
  6. [Study on occurrence of anterior ankle pain after distal tibial extra-articular fractures treated with retrograde tibial intramedullary nail].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
  7. The masquelet technique for severe open fractures: current insights.Journal of orthopaedic surgery and research · 2026
    Review
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaobin LiDepartment of Traumatic Orthopedics, Yuncheng Central Hospital affiliated to Shanxi Medical University, Yuncheng, Shanxi Province, 044000, China.
Kaipeng ChenDepartment of Traumatic Orthopedics, Yuncheng Central Hospital affiliated to Shanxi Medical University, Yuncheng, Shanxi Province, 044000, China.
Haipeng XueDepartment of Traumatic Orthopedics, Yuncheng Central Hospital affiliated to Shanxi Medical University, Yuncheng, Shanxi Province, 044000, China.
Junwen ChengDepartment of Traumatic Orthopedics, Yuncheng Central Hospital affiliated to Shanxi Medical University, Yuncheng, Shanxi Province, 044000, China.
Xiaoping YuDepartment of Clinical Laboratory, Yuncheng Central Hospital affiliated to Shanxi Medical University, No. 3690, Hedong East Street, Yanhu District, Yuncheng, Shanxi Province, 044000, China. yuppdt@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary nail (IMN) and plate fixation are the most commonly used surgical modalities for distal tibia fractures. However, the superiority of their efficacy regarding functional outcomes and complications remains controversial. Here, we performed a systematic review and meta-analysis to compare the efficacy of these two modalities.

methodsRandomized controlled trials (RCTs) comparing the efficacy of IMN and plate fixation in distal tibia fractures were searched in PubMed, Web of Science, EMBASE, ClinicalTrials.gov, and Cochrane Library up to January 31, 2024. Weighted mean difference (WMD) and odds ratio (OR) with corresponding 95% confidence interval (CI) were estimated using a random-effect model for continuous and categorical outcomes, respectively.

resultsA total of 20 RCTs comprising 1528 patients were included. Compared with plate fixation, IMN significantly shortened surgery time (WMD=-10.73 min, 95%CI: -15.93 to -5.52), union time (WMD=-1.56 weeks, 95%CI: -2.82 to -0.30), and partial (WMD=-1.71 weeks, 95%CI: -1.91 to -0.43) and full (WMD=-2.61 weeks, 95%CI: -3.53 to -1.70) weight-bearing time. IMN was associated with markedly reduced risk of wound infection (OR = 0.44, 95%CI: 0.31-0.63) and secondary procedures (OR = 0.72, 95%CI: 0.55-0.95), but increased the risk of malunion (OR = 1.53, 95%CI: 1.02-2.30) and anterior knee pain (OR = 3.94, 95%CI: 1.68-9.28). The rates of nonunion, delayed union, and functional assessment scores did not significantly differ between the two groups. The percentages of patients obtaining an excellent functional outcome or an excellent and good functional outcome post-operation were comparable.

conclusionsBoth IMN and plate fixation are effective modalities for the surgical treatment of distal tibia fractures. IMN seems to be preferred since it confers more advantages, but the elevated rates of malunion and knee pain require attention. The decision on fixation modality should be tailored to the specific fracture, considering these pros and cons.

Indexed as

Bone PlatesFracture Fixation, IntramedullaryRandomized Controlled Trials as TopicTibial FracturesAdultBone NailsFemaleFracture Fixation, InternalHumansMaleMiddle AgedOperative TimePostoperative ComplicationsTreatment OutcomeComplicationDistal tibia fracturesInfectionIntramedullary nail fixationMeta-analysisPlate fixation

Identifiers

PMID38997735
PMCPMC11241967

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.