Evidence map›Paper›PMID 38997699›Full record

SynthesisBMC oral health2024

Maternal smoking during pregnancy and early childhood dental caries in children: a systematic review and meta-analysis.

Dorsa Samani, SeyedMehdi Ziaei, Farhan Musaie, Hooman Mokhtari, Rubina Valipour, Mahsa Etemadi, Narin Gharehdaghi, Seyede Fateme Rezaei, Soheil Raji, Tara Fazel and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Association between passive smoking and oral health among children: an umbrella review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dorsa Samani *Tabriz University of Medical Sciences, Tabriz, Iran.
SeyedMehdi Ziaei *Hamadan University of Medical Sciences, Hamadan, Iran.
Farhan Musaie *Dental Branch, Islamic Azad University, Tehran, Iran.
Hooman MokhtariFaculty of Dentistry, Babol University of Medical Sciences, Babol, Iran.
Rubina ValipourFaculty of Dentistry, Semmelweis University, Budapest, Hungary.
Mahsa EtemadiDepartment of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Narin GharehdaghiFaculty of Dentistry, Istanbul Okan University, Tuzla Campus Tuzla, Istanbul, 34959, Turkey.
Seyede Fateme RezaeiSchool of Dentistry, Mazandaran University of medical sciences, Dentist, Sari, Iran.
Soheil RajiFaculty of Dentistry, Van Yüzüncü Yıl University, Van, Türkiye, Turkey.
Tara FazelStudent Research Committee, School of International Campus, Guilan University of Medical Sciences, Rasht, Iran.
Alireza Mokhtari SakhvidiDental Faculty, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Dralirezamokhtari95@gmail.com.
Niloofar DeraviStudent Research Committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. niloofarderavi@sbmu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly childhood dental caries, or ECC, is a significant global oral health concern associated with various adverse outcomes. This systematic review and meta-analysis aimed to investigate the potential link between maternal smoking during pregnancy and the occurrence of dental caries in children.

methodThrough a comprehensive search of PubMed, Scopus, and Google Scholar databases for studies examining the correlation between maternal smoking during pregnancy and childhood caries, we identified 609 relevant articles up to October 2023. Studies were selected, and data extraction was based on the pre-established eligibility criteria and items. Meta-analysis was executed utilizing Comprehensive Meta-analysis (CMA) with a random effects model, ensuring a robust synthesis of the gathered evidence.

result7 cohorts and five cross-sectional studies, totaling 12 studies, were included in our analysis. The combined results from the studies revealed a significant association between maternal smoking during pregnancy and an increased risk of dental caries in children (OR = 1.78, 95% CI = 1.55-2.05, I2 = 68.53). Sensitivity analyses confirmed the reliability of our results. However, there were indications of publication bias, as suggested by the funnel plot and Egger's test (P = 0.011) concerning the connection between prenatal smoking and childhood caries.

conclusionThis review underscores the association between maternal smoking during pregnancy and childhood dental caries. Nevertheless, confounding variables influence this link, necessitating more large-scale, longitudinal studies with adjusted factors. Additional randomized control trials are needed to validate these findings due to the observed heterogeneity. Future research should investigate the precise reasons behind this association. It is essential to raise awareness among pregnant women about the risks of smoking through educational programs.

Indexed as

Dental CariesPrenatal Exposure Delayed EffectsSmokingChildChild, PreschoolFemaleHumansPregnancyChildrenDental cariesMaternal smokingMeta-analysisPregnancySystematic review

Identifiers

PMID38997699
PMCPMC11241989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.