Evidence map›Paper›PMID 38997644›Full record

ArticleBMC ophthalmology2024

Blepharoptosis and corneal epithelial thickness alterations, is there any relation?

Seyed Mohsen Rafizadeh, Seyed Ali Sonbolestan, Haniyeh Zeidabadinejad, Mohammad-Ali Abtahi

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Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Seyed Mohsen RafizadehDepartment of oculo-facial plastic and reconstructive Surgery, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Ali SonbolestanDepartment of oculo-facial plastic and reconstructive Surgery, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran. sonbolestan@gmail.com.
Haniyeh ZeidabadinejadFarabi Hospital, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad-Ali AbtahiDepartment of cornea and anterior segment, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the epithelial thickness map of ptotic eyes of blepharoptosis patients with contralateral non- ptotic eyes.

methodsUnilateral blepharoptosis patients were enrolled consecutively. Patients were underwent full ophthalmologic examination and their demographic data such as age and gender and specific ptosis findings e.g. the cause and duration, MRD-1, and levator palpebralis superioris function were registered. Anterior segment imaging for epithelial thickness measurements was done using the Avanti RTVue-XR platform. The corneal epithelial thickness maps of ptotic and non-ptotic eyes were compared.

results44 patients with unilateral blepharoptosis were included in the study. 27 (61.4%) of them were female and 17 (38.6%) cases were male. The mean of the patients' ages was 24.40 ± 15.16 years. Ptotic eyes had significantly thinner superior (p = 0.000), superior-temporal (p = 0.000) and superior-nasal (p = 0.005) sectors of the cornea and slightly thicker corneal epithelium (CE) in the inferior-nasal sector. The correlation of difference of superior-inferior CE was evaluated with different parameters including patient's age (p = 0.457), type of blepharoptosis (p = 0.786), duration of blepharoptosis (p = 0.477) and MRD1 (p = 0.248), but no correlation was found.

conclusionsThis study revealed that lid position in blepharoptosis may have effects on the corneal epithelial thickness map. Because of the lower position of upper eyelid, a thinning effect on superior corneal sectors may happen.

Indexed as

BlepharoptosisEpithelium, CornealAdolescentAdultAgedChildChild, PreschoolFemaleHumansMaleMiddle AgedYoung AdultBlepharoptosisCorneal epithelial thickness

Identifiers

PMID38997644
PMCPMC11241861

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