Evidence map›Paper›PMID 38997629›Full record

ArticleBMC microbiology2024

An altered uterine microbiota with endometrial hyperplasia.

Xue Ying, Gufeng Xu, Huiyun Wang, Yue Wang

Abstract read
In one paragraph

Article in BMC microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xue Ying *Department of Ambulatory Surgery, Women's Hospital, Zhejiang University School of Medicine, China. 1 Xueshi Road, Hangzhou, Zhejiang, 310006, P.R. China.
Gufeng Xu *Department of Ambulatory Surgery, Women's Hospital, Zhejiang University School of Medicine, China. 1 Xueshi Road, Hangzhou, Zhejiang, 310006, P.R. China.
Huiyun WangDepartment of Ambulatory Surgery, Women's Hospital, Zhejiang University School of Medicine, China. 1 Xueshi Road, Hangzhou, Zhejiang, 310006, P.R. China.
Yue WangDepartment of Ambulatory Surgery, Women's Hospital, Zhejiang University School of Medicine, China. 1 Xueshi Road, Hangzhou, Zhejiang, 310006, P.R. China. misswangyue@zju.edu.cn.

Funding

Natural Science Foundation of Zhejiang Province LGF22H040011the Health Commission of Zhejiang Province 2022KY857Zhejiang Provincial Department of Education Y202146852
6 · The paper itself

Abstract

backgroundEndometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear.

resultsThe present study investigated the uterine microbiome in patients with benign uterine conditions and endometrial hyperplasia. A significant structural shift in the uterine microbiome of patients with endometrial hyperplasia compared to those with benign conditions was found. Delftia, Serratia and Stenotrophomonas were significantly enriched in endometrial hyperplasia samples and associated with the presence of endometrial hyperplasia.

conclusionsThe novel finding suggested that increased abundance of Delftia, Serratia and Stenotrophomonas is associated with the presence of endometrial hyperplasia. Further investigation is needed to determine the value of these microbes as biomarkers for endometrial hyperplasia.

Indexed as

BacteriaEndometrial HyperplasiaMicrobiotaUterusAdultFemaleHumansMiddle AgedRNA, Ribosomal, 16SSerratiaStenotrophomonasRNA, Ribosomal, 16S16S rDNADelftiaEndometrial hyperplasiaMicrobiomeSerratiaStenotrophomonasUterus

Identifiers

PMID38997629
PMCPMC11242002

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.