Evidence map›Paper›PMID 38997604›Full record

ReviewWorld journal of pediatrics : WJP2024

Differentiating rhythmic high-amplitude delta with superimposed (poly) spikes from extreme delta brushes: limitations of standardized nomenclature and implications for patient management.

Rene Andrade-Machado, Elham Abushanab, Namrata D Patel, Avantika Singh

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Review in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rene Andrade-MachadoChildren's Hospital of Wisconsin Wauwatosa: Milwaukee, 8915 W Connell Ct, Milwaukee, WI, 53226, USA. randrade-machado@mcw.edu.ORCID 0000-0002-0970-4990
Elham AbushanabChildren's Hospital of Wisconsin Wauwatosa: Milwaukee, 8915 W Connell Ct, Milwaukee, WI, 53226, USA.
Namrata D PatelChildren's Hospital of Wisconsin Wauwatosa: Milwaukee, 8915 W Connell Ct, Milwaukee, WI, 53226, USA.
Avantika SinghChildren's Hospital of Wisconsin Wauwatosa: Milwaukee, 8915 W Connell Ct, Milwaukee, WI, 53226, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFollowing the standardized nomenclature proposed by the American Clinical Neurophysiology Society (ACNS), rhythmic high-amplitude delta activity with superimposed spikes (RHADS) can be reported as an extreme delta brush (EDB). The clinical implications of similar electrographic patterns being reported as RHADS versus EDB are important to highlight. We aim to review the electrographic characteristics of RHADS, evaluate whether RHADS is seen in other neurological disorders, and identify the similar and unique characteristics between RHADS and EDB to ultimately determine the most accurate way to differentiate and report these patterns. We believe that the differentiation of RHADS and EDB is important as there is a vast difference in the diagnostic approach and the medical management of associated underlying etiologies. DATA SOURCE: We conducted an extensive search on MEDLINE and Pubmed utilizing various combinations of keywords. Searching for "gamma polymerase and EEG", or "RHADS" or "Alpers syndrome and EEG" or "EEG" AND "Alpers-Huttenlocher syndrome".

resultsThree articles were found to be focused on the description of "RHADS" pattern in Alpers Syndrome. No publication to date were found when searching for the terms "EDB" AND "children", AND "infant" AND "adolescent" excluding "encephalitis" and "neonate". Although RHADS and EDB appear as similar EEG patterns, meticulous analysis can differentiate them. RHADS is not exclusive to patients with Alpers-Huttenlocher syndrome and may manifest in regions beyond the posterior head region. Reactivity to eye-opening and response to anesthesia can be two other elements that help in the differentiation of these patterns.

conclusionRHADS is not exclusive to patients with AHS and may manifest in regions beyond the posterior head region. Reactivity to eye-opening and response to anesthesia are features that help in the differentiation of these patterns.

Indexed as

Delta RhythmElectroencephalographyTerminology as TopicAdolescentChildDiagnosis, DifferentialHumansInfantAlpers–Huttenlocher syndromeAutoimmune encephalitisExtreme delta brushNeurological disorderPolyspikeRhythmic delta activityRhythmic high-amplitude delta activitySeizure

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.