Evidence map›Paper›PMID 38997419›Full record

ArticleCommunications biology2024

A type II phosphatidylinositol-4-kinase coordinates sorting of cargo polarizing by endocytic recycling.

Anezia Kourkoulou, Olga Martzoukou, Reinhard Fischer, Sotiris Amillis

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. VapA/Scs2 sustains polarized growth inMicrobial cell (Graz, Austria) · 2026
    Article
  4. Regulation of yeast polarized exocytosis by phosphoinositide lipids.Cellular and molecular life sciences : CMLS · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anezia KourkoulouNational and Kapodistrian University of Athens, Department of Biology, Athens, Hellas, Greece.
Olga MartzoukouNational and Kapodistrian University of Athens, Department of Biology, Athens, Hellas, Greece.ORCID 0000-0001-5445-484X
Reinhard FischerKarlsruhe Institute of Technology - South Campus, Institute for Applied Biosciences, Department of Microbiology, Karlsruhe, Germany.
Sotiris AmillisNational and Kapodistrian University of Athens, Department of Biology, Athens, Hellas, Greece. samillis@biol.uoa.gr.ORCID 0009-0001-8472-0018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depending on their phosphorylation status, derivatives of phosphatidylinositol play important roles in vesicle identity, recognition and intracellular trafficking processes. In eukaryotic cells, phosphatidylinositol-4 phosphate pools generated by specific kinases are key determinants of the conventional secretion pathways. Earlier work in yeast has classified phosphatidylinositol-4 kinases in two types, Stt4p and Pik1p belonging to type III and Lsb6p to type II, with distinct cellular localizations and functions. Eurotiomycetes appear to lack Pik1p homologues. In Aspergillus nidulans, unlike homologues in other fungi, AnLsb6 is associated to late Golgi membranes and when heterologously overexpressed, it compensates for the thermosensitive phenotype in a Saccharomyces cerevisiae pik1 mutant, whereas its depletion leads to disorganization of Golgi-associated PH

Indexed as

1-Phosphatidylinositol 4-KinaseEndocytosisGolgi ApparatusSaccharomyces cerevisiaeAspergillus nidulansFungal ProteinsPhosphatidylinositol PhosphatesProtein TransportSaccharomyces cerevisiae Proteins1-Phosphatidylinositol 4-KinaseFungal Proteinsphosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesPIK1 protein, S cerevisiaeSaccharomyces cerevisiae Proteins

Identifiers

PMID38997419
PMCPMC11245547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.