SynthesisChinese medical journal2025
Is unicompartmental knee arthroplasty a better choice than total knee arthroplasty for unicompartmental osteoarthritis? A systematic review and meta-analysis of randomized controlled trials.
Synthesis in Chinese medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of the clinical efficacy of lateral versus medial unicondylar replacement for unicompartmental osteoarthritis of the knee: a meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Efficacy and Safety of Adding 1 μg/Kg Dexmedetomidine to 20 ml Bupivacaine in Supraclavicular Brachial Plexus Block: A Randomized Trial.Current drug safety · 2025Trial
- Patient-reported outcomes after lateral unicompartmental and total knee arthroplasty: a propensity score-matched cohort study.Archives of orthopaedic and trauma surgery · 2026Article
- Osteoarthritis: Epidemiology, Diagnosis, and Treatment.MedComm · 2026Review
- Mako robot-assisted unicompartmental knee arthroplasty mitigates the impact of surgeon handedness.Journal of robotic surgery · 2026Article
- Article
- Portable electronic devices for mechanotherapy and operative treatment of osteoarthritis.Mechanobiology in medicine · 2026Review
- Comparative efficacy of total knee arthroplasty versus unicompartmental knee arthroplasty in obese patients with medial knee osteoarthritis.Frontiers in medicine · 2026Article
- Early institutional adoption and outcomes from 154 consecutive medial mobile-bearing unicompartmental knee arthroplasties: a single-center experience after implant introduction.Archives of orthopaedic and trauma surgery · 2025Article
- Demographic and Clinical Determinants of Unicondylar Vs Total Knee Arthroplasty Selection.Arthroplasty today · 2025Article
- Robotic-Assisted Joint Line Preserving Unicompartmental Knee Arthroplasty Positioning Among Octogenarians.Journal of personalized medicine · 2025Article
- Patients with Robotic Arm-Assisted Medial Unicompartmental Knee Arthroplasty (mUKA) Regain Their Preoperative Activity Level Two Weeks Earlier Compared to Robotic Arm-Assisted Kinematically Aligned Total Knee Arthroplasty (rKA-TKA).Sensors (Basel, Switzerland) · 2025Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe choice of unicompartmental knee arthroplasty (UKA) vs . total knee arthroplasty (TKA) in the surgical treatment of knee osteoarthritis (KOA) remains controversial. This study aimed to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) to compare the clinical results of UKA and TKA for treating unicompartmental KOA.
methodsPubMed, Embase, and the Cochrane Library were systematically searched for articles published up to January 2, 2023. The literature was rigorously screened to include only RCTs comparing UKA and TKA for unicompartmental KOA. A systematic review and meta-analysis were performed to calculate the mean difference (MD), relative risk (RR), and 95% confidence interval (CI) according to the Cochrane standards.
resultsThirteen publications involving 683 UKAs and 683 TKAs were analyzed. Except for one study with a follow-up period of 15 years, all outcome measures reported were within 5 years of follow-up. Meta-analysis showed better knee recovery (MD: 1.23; 95% CI: 1.01-1.45; P <0.001), greater knee function (MD: 1.78; 95% CI: 0.34-3.22; P = 0.020), less pain (MD: 0.75; 95% CI: 0.43-1.06; P <0.001), and better health status (MD: 3.75; 95% CI: 0.81-6.69; P = 0.010) after UKA than TKA. However, considering the minimal clinically important difference values for these variables, the findings were not clinically relevant. Moreover, UKA patients had fewer complications (RR: 0.59; 95% CI: 0.45-0.78; P <0.001) and shorter hospital stays (MD: -0.89; 95% CI: -1.57 to -0.22; P = 0.009) than did TKA patients. There were no statistically significant differences in terms of postoperative range of movement, revision, failure, operation time, and patient satisfaction.
conclusionsIn terms of clinical efficacy, there was no obvious advantage of UKA over TKA in the surgical treatment of knee OA when considering the minimal clinically important difference. The main advantage of UKA over TKA is that it leads to fewer complications and a shorter length of hospital stay. It is ideal to perform prospective studies with longer follow-up periods to fully evaluate the long-term efficacy and safety of the two procedures in the future.
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