Evidence map›Paper›PMID 38997123›Full record

ArticleAJNR. American journal of neuroradiology2025

Incorporation of Edited MRS into Clinical Practice May Improve Care of Patients with

Lucia Nichelli, Capucine Cadin, Patrizia Lazzari, Bertrand Mathon, Mehdi Touat, Marc Sanson, Franck Bielle, Małgorzata Marjańska, Stéphane Lehéricy, Francesca Branzoli

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucia NichelliFrom the Department of Neuroradiology (L.N., P.L., S.L.), La Pitié Salpêtrière University Hospital, Assistance publique-hôpitaux de Paris, Paris, France lucia.nichelli@aphp.fr.
Capucine CadinThe Paris Brain Institute (L.N., C.C., B.M., M.T., M.S., F. Bielle, S.L., F. Branzoli), Sorbonne University, Institut national de la santé et de la Recherche Médicale 1127, Centre National de la Recherche Scientifique, Joint Research Unit 7225, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.
Patrizia LazzariFrom the Department of Neuroradiology (L.N., P.L., S.L.), La Pitié Salpêtrière University Hospital, Assistance publique-hôpitaux de Paris, Paris, France.
Bertrand MathonDepartment of Neurosurgery (B.M.), La Pitié Salpêtrière University Hospital, Paris, France.ORCID 0000-0002-9182-5846
Mehdi TouatDepartment of Neuro-oncology (M.T., M.S.), La Pitié Salpêtrière University Hospital, Paris, France.
Marc SansonDepartment of Neuro-oncology (M.T., M.S.), La Pitié Salpêtrière University Hospital, Paris, France.
Franck BielleThe Paris Brain Institute (L.N., C.C., B.M., M.T., M.S., F. Bielle, S.L., F. Branzoli), Sorbonne University, Institut national de la santé et de la Recherche Médicale 1127, Centre National de la Recherche Scientifique, Joint Research Unit 7225, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.
Małgorzata MarjańskaCenter for Magnetic Resonance Research (M.M.), Department of Radiology, University of innesota, Minneapolis, Minnesota.
Stéphane LehéricyFrom the Department of Neuroradiology (L.N., P.L., S.L.), La Pitié Salpêtrière University Hospital, Assistance publique-hôpitaux de Paris, Paris, France.
Francesca BranzoliThe Paris Brain Institute (L.N., C.C., B.M., M.T., M.S., F. Bielle, S.L., F. Branzoli), Sorbonne University, Institut national de la santé et de la Recherche Médicale 1127, Centre National de la Recherche Scientifique, Joint Research Unit 7225, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIsocitrate dehydrogenase ( MATERIALS AND

methodsSubjects with presumed low-grade gliomas eligible for surgery (cohort 1) and subjects with

resultsThirty-four consecutive subjects were enrolled. Due to poor spectra quality and lack of histologic specimens, data from 26 subjects were analyzed. Twenty-one belonged to cohort 1 (11 women; median age, 42 years); and 5, to cohort 2 (3 women; median age, 48 years). Edited MR spectroscopy showed 100% specificity for detection of

conclusionsOur results, acquired in a clinic setting, confirmed that edited MR spectroscopy is highly specific for both

Indexed as

Brain NeoplasmsGliomaIsocitrate DehydrogenaseMagnetic Resonance SpectroscopyMutationAdultAgedFemaleGlutaratesHumansMaleMiddle AgedProspective StudiesYoung Adultalpha-hydroxyglutarateGlutaratesIsocitrate Dehydrogenase

Identifiers

PMID38997123
PMCPMC11735446

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.