ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024
Retrospective Analysis of Cholera/Acute Watery Diarrhea Outbreaks in Ethiopia From 2001 To 2023: Incidence, Case Fatality Rate, and Seasonal and Multiyear Epidemic Patterns.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cholera burden in Ghana: a systematic review and meta-analysis of prevalence, antimicrobial resistance and risk factors.International health · 2025Pooled it
- Determinants of recovery time from cholera in a conflict-affected agro-pastoral region of ethiopia: evidence from survival models.Conflict and health · 2026Article
- Epidemiological evaluation of cholera outbreak dynamics in conflict-affected Central and Northwestern Tigray, northern Ethiopia: evidence from GEE analysis.Epidemiology and infection · 2026Article
- Risk Communication and Community Engagement (RCCE) implementations to control cholera outbreak in Oromia region, Ethiopia.Tropical medicine and health · 2025Article
- Coverage of Two-Dose Preemptive Cholera Mass Vaccination Campaign in High-Priority Hotspots in Shashemene, Oromia Region, Ethiopia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Dissecting Water, Sanitation, and Hygiene (WaSH) to Assess Risk Factors for Cholera in Shashemene, Oromia Region, Ethiopia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Ethiopia National Cholera Elimination Plan 2022-2028: Experiences, Challenges, and the Way Forward.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- National and Subnational Burden of Cholera in Ethiopia, 2019 to 2023: Findings From the Global Burden of Diseases Study 2023.Inquiry : a journal of medical care organization, provision and financingArticle
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17 authors.
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Abstract
backgroundThe Ethiopian government has developed the multisectoral cholera elimination plan (NCP) with an aim of reducing cholera incidence and case fatality rate (CFR). To better understand and monitor the progress of this plan, a comprehensive review of national cholera epidemiology is needed.
methodsReported data on cholera/acute watery diarrhea (AWD) cases in the past 20 years were extracted from the Ethiopian Public Health Institute and World Health Organization databases. Descriptive statistics, Pearson χ2, and logistic regression analyses were conducted.
resultsFrom January 2001 to November 2023, a total of 215 205 cholera/AWD cases, 2355 deaths with a cumulative CFR of 1.10% (95% confidence interval [CI], 1.092-1.095), and a mean annual incidence rate of 8.9/100 000 (95% CI, 6.5-11.3) were reported. Two major upsurges of cholera epidemics were found in the last two decades with mean attack rate (AR) of 20.57/100 000 in 2006-2010 and 14.83/100 000 in 2016-2020. Another resurgence of outbreaks occured in 2021-2023 (mean AR, 8.63/100 000). In 2015-2023, 54.0% (53 990/99 945) of cases were aged 15-44 years. National cholera CFR (3.13% [95% CI: 2.1-4.5]) was the highest in 2022. The 2015-2023 cumulative cholera CFR was different across regions: Benishangul Gumuz (6.07%), Gambela (1.89%), Sidama (1.42%), Southern Nation, Nationalities, and Peoples' (1.34%), Oromia (1.10%), and Amhara (1.09%). Cholera/AWD patients in older adults (≥45 years), severe dehydration, peak rainy season (June-August), and outpatients were associated with higher risk of death.
conclusionsCholera has been a public health problem in Ethiopia with case fatalities still above the global target. Case management needs to be improved particularly in outpatients and older populations. Outbreak preparedness should be rolled out well in advance of the typical rainy seasons. Significant investments are essential to advance the cholera surveillance system at healthcare setting and community level. Underlying factors of cholera deaths per areas should be further investigated to guide appropriate interventions to meet the NCP target by 2028.
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