Evidence map›Paper›PMID 38995674›Full record

ArticleThe Journal of general virology2024

Comparative pathogenesis of three Mayaro virus genotypes in the cynomolgus macaque.

Melissa M Hamilton, Emily M Webb, Max C Peterson, Grishma Patel, Maciel Porto, Tatyana Orekov, Jesse H Erasmus, Brad Finneyfrock, Anthony Cook, Albert J Auguste and 1 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Melissa M HamiltonBIOQUAL Inc., Rockville, MD, 20852, USA.
Emily M WebbDepartment of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA.
Max C PetersonBIOQUAL Inc., Rockville, MD, 20852, USA.
Grishma PatelBIOQUAL Inc., Rockville, MD, 20852, USA.
Maciel PortoBIOQUAL Inc., Rockville, MD, 20852, USA.
Tatyana OrekovBIOQUAL Inc., Rockville, MD, 20852, USA.
Jesse H ErasmusHDT Bio, Seattle, WA, 98102, USA.
Brad FinneyfrockBIOQUAL Inc., Rockville, MD, 20852, USA.
Anthony CookBIOQUAL Inc., Rockville, MD, 20852, USA.
Albert J AugusteDepartment of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA.
Swagata KarBIOQUAL Inc., Rockville, MD, 20852, USA.

Funding

A Novel Strategy for Generating Safe and Effective Flavivirus VaccinesR01AI153433 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI AUGUSTE, ALBERT J. · 2020 to 2024
$2.0M
NIAID NIH HHS R01 AI153433
6 · The paper itself

Abstract

Mayaro virus (MAYV), a mosquito-borne alphavirus, is considered an emerging threat to public health with epidemic potential. Phylogenetic studies show the existence of three MAYV genotypes. In this study, we provide a preliminary analysis of the pathogenesis of all three MAYV genotypes in cynomolgus macaques (

Indexed as

AlphavirusAlphavirus InfectionsGenotypeMacaca fascicularisRNA, ViralViremiaAnimalsAntibodies, NeutralizingAntibodies, ViralCytokinesDisease Models, AnimalPhylogenyAntibodies, NeutralizingAntibodies, ViralCytokinesRNA, Viralalphaviruscynomolgus macaqueMayaro virusMAYV pathogenesisnon-human primate model

Identifiers

PMID38995674
PMCPMC13291939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.