Evidence map›Paper›PMID 38995434›Full record

ArticleBiological trace element research2025

Underlying Mechanism of Fluoride Inhibits Colonic Gland Cells Proliferation by Inducing an Inflammation Response.

Jing Liu, Jing Zhao, Yu-Ling Zhang, Cai Zhang, Guo-Dong Yang, Wei-Shun Tian, Bian-Hua Zhou, Hong-Wei Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing LiuHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Jing ZhaoHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Yu-Ling ZhangHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Cai ZhangHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Guo-Dong YangHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Wei-Shun TianHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Bian-Hua ZhouHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China.
Hong-Wei WangHenan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Luoyang, Henan, 471000, People's Republic of China. wanghw@haust.edu.cn.

Funding

National Natural Science Foundation of China 32102740National Natural Science Foundation of China 32373084
6 · The paper itself

Abstract

The integrity of colonic gland cells is a prerequisite for normal colonic function and maintenance. To evaluate the underlying injury mechanisms in colonic gland cells induced by excessive fluoride (F), forty-eight female Kunming mice were randomly allocated into four groups and treated with different concentrations of NaF (0, 25, 50, and 100 mg F

Indexed as

Cell ProliferationColonFluoridesInflammationAnimalsFemaleIntestinal MucosaMiceNF-kappa BSignal TransductionFluoridesNF-kappa BColonFluorideInflammationJAK/STAT signalingNF-κBProliferation

Identifiers

PMID38995434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.