Evidence map›Paper›PMID 38995393›Full record

ArticleNeuroradiology2024

Automated classification of brain MRI reports using fine-tuned large language models.

Jun Kanzawa, Koichiro Yasaka, Nana Fujita, Shin Fujiwara, Osamu Abe

Abstract read
In one paragraph

Article in Neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  8. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jun KanzawaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Koichiro YasakaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan. koyasaka@gmail.com.ORCID http://orcid.org/0000-0002-0324-6562
Nana FujitaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Shin FujiwaraDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Osamu AbeDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the efficacy of fine-tuned large language models (LLM) in classifying brain MRI reports into pretreatment, posttreatment, and nontumor cases.

methodsThis retrospective study included 759, 284, and 164 brain MRI reports for training, validation, and test dataset. Radiologists stratified the reports into three groups: nontumor (group 1), posttreatment tumor (group 2), and pretreatment tumor (group 3) cases. A pretrained Bidirectional Encoder Representations from Transformers Japanese model was fine-tuned using the training dataset and evaluated on the validation dataset. The model which demonstrated the highest accuracy on the validation dataset was selected as the final model. Two additional radiologists were involved in classifying reports in the test datasets for the three groups. The model's performance on test dataset was compared to that of two radiologists.

resultsThe fine-tuned LLM attained an overall accuracy of 0.970 (95% CI: 0.930-0.990). The model's sensitivity for group 1/2/3 was 1.000/0.864/0.978. The model's specificity for group1/2/3 was 0.991/0.993/0.958. No statistically significant differences were found in terms of accuracy, sensitivity, and specificity between the LLM and human readers (p ≥ 0.371). The LLM completed the classification task approximately 20-26-fold faster than the radiologists. The area under the receiver operating characteristic curve for discriminating groups 2 and 3 from group 1 was 0.994 (95% CI: 0.982-1.000) and for discriminating group 3 from groups 1 and 2 was 0.992 (95% CI: 0.982-1.000).

conclusionFine-tuned LLM demonstrated a comparable performance with radiologists in classifying brain MRI reports, while requiring substantially less time.

Indexed as

Brain NeoplasmsMagnetic Resonance ImagingSensitivity and SpecificityFemaleHumansMaleRetrospective StudiesBrain tumorLarge language modelMagnetic resonance imagingNatural language processing

Identifiers

PMID38995393
PMCPMC11611921

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.