Evidence map›Paper›PMID 38995318›Full record

ArticleJournal of gastrointestinal cancer2024

Hepatocellular Carcinoma in Asia: Physician and Patient Perspectives on Surveillance, Diagnosis, and Treatment.

Rosmawati Mohamed, Wendy Wang, Tawesak Tanwandee, Irsan Hasan, Cam Phuong Pham, Young-Suk Lim, Sheng-Nan Lu, Murallitharan Munisamy, Thi Thanh Huong Tran, Evy Ratnawati and 3 more

Abstract read
In one paragraph

Article in Journal of gastrointestinal cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rosmawati Mohamed *University of Malaya, Kuala Lumpur, Malaysia.
Wendy Wang *Liver Disease Prevention and Treatment Research Foundation, Taipei, Taiwan.
Tawesak TanwandeeDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Irsan HasanFaculty of Medicine, University Indonesia/Ciptomangunkusumo Hospital, Jakarta, Indonesia.
Cam Phuong PhamNuclear Medicine and Oncology Center, Bach Mai Hospital, Department of Nuclear Medicine, HaNoi Medical University, Hanoi, Vietnam.
Young-Suk LimDepartment of Internal Medicine and Department of Gastroenterology, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Sheng-Nan LuDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Murallitharan MunisamyNational Cancer Society of Malaysia, Sunway University, 66 Jalan Raja Muda Abdul Aziz, 50300, Kuala lumpur, Malaysia.
Thi Thanh Huong TranNational Cancer Institute, Hanoi Medical University, Hanoi, Vietnam.
Evy RatnawatiIndonesian Cancer Information and Support Center (CISC), Jakarta, Indonesia.
Wattana SukeepaisarnjaroenFaculty of Medicine and Department of Medicine, Gastrointestinal Unit, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
Mahir KarababaMedical Affairs, COR2ED, Basel, Switzerland.
Chee-Kiat TanDepartment of Gastroenterology and Hepatology, Singapore General Hospital, Academia, 20 College Road, Singapore, 169856, Singapore. tan.chee.kiat@singhealth.com.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn several Asian countries, hepatocellular carcinoma (HCC) is a leading cause of cancer deaths. HCC risk factors in Asia differ from those elsewhere and are changing with the treatment landscape as systemic treatment options increase. This study was conducted to gain insight from physicians and patients into HCC screening, diagnosis, and treatment strategies in Indonesia, Korea, Malaysia, Singapore, Taiwan, Thailand, and Vietnam.

methodsTwo cross-sectional, anonymized, online surveys were completed between July and December 2022 by physicians diagnosing and treating HCC (55 questions on risk factors, surveillance, diagnosis, and treatment) and patients ≥ 18 years old diagnosed with HCC (36 questions on disease knowledge, quality of life, and experiences of diagnosis and treatment).

resultsResponses were received from 276 physicians in all 7 countries and 130 patients in Thailand, Taiwan, and Vietnam. From the physician's perspective, surveillance programs are widespread but identify insufficient HCC cases; only 18% are early-stage HCC at diagnosis. From the patient's perspective, knowledge of risk factors increases after diagnosis, but few seek support from patient associations; patients would benefit from better communication from their doctors. Treatment affordability and side effects are key issues for patients.

conclusionsAwareness of the risk factors for HCC should be raised in primary care and the general population, and surveillance should identify early-stage HCC. Because patients rely on their doctors for support, doctors should better understand their patients' needs, and patients could be supported by trained nurses or case managers. Programs are needed to increase patients' access to proven HCC treatments.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdultAgedAsiaCross-Sectional StudiesEarly Detection of CancerFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPhysiciansQuality of LifeRisk FactorsSurveys and QuestionnairesAsiaDiagnosisHepatocellular CarcinomaSurveys and questionnairesTherapeutics

Identifiers

PMID38995318
PMCPMC11347480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.