Evidence map›Paper›PMID 38995317›Full record

ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2025

Exploring neurocognitive features in adolescents and young adults with anorexia nervosa: Evidence from a longitudinal study.

Tanja Wittek, Michael Zeiler, Stefanie Truttmann, Julia Philipp, Konstantin Kopp, Helene Krauss, Ellen Auer-Welsbach, Suanne Ohmann, Petra Sackl-Pammer, Sonja Werneck-Rohrer and 7 more

Abstract read
In one paragraph

Article in European eating disorders review : the journal of the Eating Disorders Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Exploring neurocognitive features in adolescents and young adults with anorexia nervosa: Evidence from a longitudinal study.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tanja WittekEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-7358-4842
Michael ZeilerEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-7087-6134
Stefanie TruttmannEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-7374-4559
Julia PhilippEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-0992-6865
Konstantin KoppEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Helene KraussEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Ellen Auer-WelsbachDepartment of Neurology and Psychiatry of Childhood and Adolescence, Clinical Centre Klagenfurt, Klagenfurt am Wörthersee, Austria.
Suanne OhmannEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-0709-0080
Petra Sackl-PammerEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Sonja Werneck-RohrerEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-9746-8141
Clarissa LaczkovicsEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0492-2286
Michaela MittererEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Andrea SchneiderEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-8194-4075
Leonie KahlenbergEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Ulrike SchmidtInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-1335-1937
Andreas KarwautzEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-9053-998X
Gudrun WagnerEating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-4845-9684

Funding

Gemeinsame Gesundheitsziele - Pharma Master Agreement - project code: 99901006800
6 · The paper itself

Abstract

objectiveWe aimed to evaluate longitudinal changes in set-shifting and central coherence in a predominantly adolescent cohort with anorexia nervosa (AN) and to explore whether these factors predict long-term eating disorder outcomes.

methodNinety-two female patients with AN (mean age: 16.2, range: 13-21 years) completed neurocognitive tests (Rey Complex Figure Test, Adapted Version of the Wisconsin Card Sorting Test) before and after 12 months of psychotherapeutic treatment (n = 45 Maudsley AN Treatment, MANTRa; n = 47 standard psychotherapy; groups not randomised). Eating disorder severity was assessed at baseline, after 6, 12 and 18 months.

resultsCentral coherence (indicated by an increase in the Rey Figure Style Index) and set-shifting (indicated by a reduction in the percentage of perseverative errors) significantly improved over the course of treatment, with similar outcomes across groups. Lower central coherence was associated with higher eating disorder severity. Individuals with lower baseline set-shifting ability tended to have worse eating disorder outcomes in the long-term. However, this trend did not reach statistical significance in a multilevel linear mixed model.

conclusionsNeurocognitive difficulties in adolescents and young adults with AN can improve after treatment. Interventions specifically addressing flexibility in thinking and behaviour may contribute to treatment success.

Indexed as

Anorexia NervosaAdolescentAdultCognitionFemaleHumansLongitudinal StudiesNeuropsychological TestsPsychotherapyTreatment OutcomeYoung Adultadolescentsanorexia nervosacentral coherencemaudsley modelset‐shifting

Identifiers

PMID38995317
PMCPMC11617805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.