Evidence map›Paper›PMID 38995003›Full record

ArticleCells2024

Hypoxia Promotes Invadosome Formation by Lung Fibroblasts.

Mégane Lebel, Dominic O Cliche, Martine Charbonneau, Karine Brochu-Gaudreau, Damien Adam, Emmanuelle Brochiero, Claire M Dubois, André M Cantin

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mégane LebelRespiratory Division, Department of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Dominic O ClicheRespiratory Division, Department of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Martine CharbonneauDepartment of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, QC J1H 5N4, Canada.
Karine Brochu-GaudreauDepartment of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0003-1163-2196
Damien AdamCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC H2X 0A9, Canada.
Emmanuelle BrochieroCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC H2X 0A9, Canada.ORCID 0000-0002-8182-943X
Claire M DuboisDepartment of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12ième Avenue Nord, Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0002-0751-2821
André M CantinRespiratory Division, Department of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

Funding

Boehringer-Ingelheim BUILD research program CRC #2018-2437CIHR RS-324683
6 · The paper itself

Abstract

Lung parenchymal hypoxia has emerged as a cardinal feature of idiopathic pulmonary fibrosis (IPF). Hypoxia promotes cancer cell invasion and metastasis through signaling that is dependent upon the lysophosphatidic acid (LPA) receptor, LPA

Indexed as

FibroblastsLungPodosomesReceptors, Lysophosphatidic AcidSignal TransductionCell HypoxiaHumansIdiopathic Pulmonary FibrosisIndolesLysophospholipidsProto-Oncogene Proteins c-aktReceptors, Platelet-Derived Growth FactorIndoleslysophosphatidic acidLysophospholipidsnintedanibProto-Oncogene Proteins c-aktReceptors, Lysophosphatidic AcidReceptors, Platelet-Derived Growth Factorfibroblastshypoxia 2idiopathic pulmonary fibrosisinvadosomes LPALPA1nintedanib

Identifiers

PMID38995003
PMCPMC11240699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.