Evidence map›Paper›PMID 38994933›Full record

ReviewCells2024

Ca

Francesco Palestra, Gina Memoli, Annagioia Ventrici, Marialuisa Trocchia, Mariarosaria Galdiero, Gilda Varricchi, Stefania Loffredo

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesco PalestraDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-6145-7475
Gina MemoliDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Annagioia VentriciDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Marialuisa TrocchiaDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Mariarosaria GaldieroDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-8086-9130
Gilda VarricchiDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-9285-4657
Stefania LoffredoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-5871-1898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IBD is an uncontrolled inflammatory condition of the gastrointestinal tract, which mainly manifests in two forms: ulcerative colitis (UC) and Crohn's disease (CD). The pathogenesis of IBD appears to be associated with an abnormal response of innate and adaptive immune cells. Innate immunity cells, such as macrophages, mast cells, and granulocytes, can produce proinflammatory (e.g., TNF-α) and oxidative stress (ROS) mediators promoting intestinal damage, and their abnormal responses can induce an imbalance in adaptive immunity, leading to the production of inflammatory cytokines that increase innate immune damage, abate intestinal barrier functions, and aggravate inflammation. Considering that Ca

Indexed as

CalciumImmunity, InnateInflammatory Bowel DiseasesAnimalsCalcium SignalingHumansCalciumCa2+-signallingCrohn’s diseasecytokinesdendritic cellsgranulocytesinflammatory bowel disease (IBD)mast cellsmonocytes/macrophagesulcerative colitis

Identifiers

PMID38994933
PMCPMC11240513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.