ArticleDevelopmental medicine and child neurology2025
Increasing prevalence of cerebral palsy in children born very preterm in Denmark.
Article in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Panorama of Cerebral Palsy in Sweden Part XIV Shows Further Decrease in Prevalence and Severity in the Birth-Years 2015-2018.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- The Impact of 40 Years of Data Collection: The Victoria Cerebral Palsy Register.Children (Basel, Switzerland) · 2026Article
- General Movements Assessment and Amiel-Tison Neurologic Examination in Neonates and Infants: Correlations and Prognostic Values Regarding Neuromotor Outcomes.Life (Basel, Switzerland) · 2026Article
- A global picture of outcomes after preterm birth: Is there a discrepancy?Developmental medicine and child neurology · 2025Article
- Very low birth weight infant outcomes in a resource-limited setting: a five-year follow-up study.Frontiers in pediatrics · 2025Article
- Increasing prevalence of cerebral palsy in children born very preterm in Denmark.Developmental medicine and child neurology · 2025Article
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Authors and funding
6 authors.
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Abstract
aimTo analyse the rising prevalence of cerebral palsy (CP) in children born preterm in Denmark.
methodWe included all live-born children born preterm in Denmark from 1997 to 2013. The prevalence of CP in children born preterm was categorized by gestational age and correlated with neonatal mortality and changes in clinical factors.
resultsAmong 70 876 children, 824 (1.2%) had CP. The overall CP prevalence in children born preterm decreased substantially until 2001, from when it increased annually by 2.8% (95% confidence interval 0.6-5.0). When categorized, the prevalence only increased significantly in children born very preterm (gestational weeks 28-31). Neonatal mortality rates decreased steadily at all gestational ages during the entire study period. Clinical factors that changed during the study period were increasing numbers of high-risk pregnancies, maternal obesity, emergency caesarean sections, neonatal admissions, and usage of assisted ventilation.
interpretationThe increasing prevalence of CP in children born preterm was driven by the subgroup born very preterm and matched their decrease in neonatal mortality. In similar population studies, decreased mortality was not followed by increased CP prevalence. An increase in clinical risk factors was unlikely to explain our findings, but more active neonatal life support may have played a role.
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