Evidence map›Paper›PMID 38994722›Full record

ArticleNMR in biomedicine2024

Hyperpolarized

Andrew J M Lewis, Michael S Dodd, Joevin Sourdon, Craig A Lygate, Kieran Clarke, Stefan Neubauer, Damian J Tyler, Oliver J Rider

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Hyperpolarized [1-Journal of magnetic resonance open · 2025
    Article
  6. Review
  7. Review
  8. Metabolic Reprogramming in Heart Failure: From Energy Starvation to Therapeutic Targets.Current treatment options in cardiovascular medicine · 2025
    Review
  9. HyperpolarizedNMR in biomedicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew J M LewisDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-3714-6711
Michael S DoddDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Joevin SourdonDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0003-4567-8256
Craig A LygateDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Kieran ClarkeDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Stefan NeubauerDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Damian J TylerDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Oliver J RiderDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Funding

Academy of Medical Sciences and the British Heart Foundation FS/14/17/30634Academy of Medical Sciences and the British Heart Foundation FS/19/18/34252Academy of Medical Sciences and the British Heart Foundation RG/13/8/30266Academy of Medical Sciences and the British Heart Foundation RG/18/12/34040BHF Oxford Centre for Research Excellence RE/18/3/34214British Heart Foundation RG/18/12/34040
6 · The paper itself

Abstract

Obesity is associated with important changes in cardiac energetics and function, and an increased risk of adverse cardiovascular outcomes. Multi-nuclear MRS and MRI techniques have the potential to provide a comprehensive non-invasive assessment of cardiac metabolic perturbation in obesity. A rat model of obesity was created by high-fat diet feeding. This model was characterized using in vivo hyperpolarized [1-

Indexed as

Energy MetabolismMyocardiumObesityAnimalsCaloric RestrictionCarbon IsotopesLiraglutideMagnetic Resonance SpectroscopyMalePhosphorus IsotopesRatsRats, Sprague-DawleyCarbon-13Carbon IsotopesLiraglutidePhosphorus Isotopesdiastolic functionhyperpolarized MRIobesity

Identifiers

PMID38994722
PMCPMC11571269

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.