Evidence map›Paper›PMID 38994584›Full record

ArticleStroke2024

Stroke Risk After Emergency Department Treat-and-Release Visit for a Fall.

Jed H Kaiser, Cenai Zhang, Hooman Kamel, Babak B Navi, Junaid Razzak, Ava L Liberman

Abstract read
In one paragraph

Article in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jed H KaiserClinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute (J.H.K., C.Z., H.K., B.B.N., A.L.L.), Weill Cornell Medicine, New York, NY.
Cenai ZhangClinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute (J.H.K., C.Z., H.K., B.B.N., A.L.L.), Weill Cornell Medicine, New York, NY.
Hooman KamelClinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute (J.H.K., C.Z., H.K., B.B.N., A.L.L.), Weill Cornell Medicine, New York, NY.
Babak B NaviClinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute (J.H.K., C.Z., H.K., B.B.N., A.L.L.), Weill Cornell Medicine, New York, NY.
Junaid RazzakDepartment of Emergency Medicine (J.R.), Weill Cornell Medicine, New York, NY.
Ava L LibermanClinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute (J.H.K., C.Z., H.K., B.B.N., A.L.L.), Weill Cornell Medicine, New York, NY.

Funding

AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenicstroke (ARCADIA)U01NS095869 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRODERICK, JOSEPH PAUL, KAMEL, HOOMAN · 2017 to 2022
$22.0M
Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)U01NS106513 · NINDS · YALE UNIVERSITY · PI Hooman Kamel, Kevin Navin Sheth · 2019 to 2026
$20.6M
MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER)R01HL144541 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, KAMEL, HOOMAN · 2019 to 2023
$3.9M
Quantitative Susceptibility Mapping for Stroke Risk Prediction of Vulnerable Carotid PlaquesR01NS123576 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Ajay Gupta, Hooman Kamel · 2022 to 2026
$3.3M
The Misdiagnosis of Cerebrovascular Disease in Emergent Headache EvaluationsK23NS107643 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LIBERMAN, AVA L · 2018 to 2022
$997k
MOLECULAR GENETICS OF ZEBRAFISH PIGMENT CELL DEVELOPMENTF32NS010764 · NINDS · UNIVERSITY OF WASHINGTON · PI LISTER, JAMES A · 1998 to 2001
$73k
NHLBI NIH HHS R01 HL144541NINDS NIH HHS F32 NS010764NINDS NIH HHS K23 NS107643NINDS NIH HHS R01 NS123576NINDS NIH HHS U01 NS095869NINDS NIH HHS U01 NS106513
6 · The paper itself

Abstract

backgroundPrevious cohort studies of hospitalized patients with a delayed diagnosis of ischemic stroke found that these patients often had an initial emergency department (ED) diagnosis of a fall. We sought to evaluate whether ED visits for a fall resulting in discharge to home (ie, treat-and-release visits) were associated with increased short-term ischemic stroke risk.

methodsA case-crossover design was used to compare ED visits for falls during case periods (0-15, 16-30, 31-90, and 91-180 days before stroke) and control periods (equivalent time periods exactly 1 year before stroke) using administrative data from the Healthcare Cost and Utilization Project on all hospital admissions and ED visits across 10 states from 2016 to 2020. To identify ED treat-and-release visits for a fall and patients hospitalized for acute ischemic stroke, we used previously validated

resultsAmong 90 592 hospitalized patients with ischemic stroke, 5230 (5.8%) had an ED treat-and-release visit for a fall within 180 days before their stroke. Patients with an ED treat-and-release visit for a fall were older (mean age, 74.7 [SD, 14.6] versus 70.8 [SD, 15.1] years), more often female (61.9% versus 53.4%), and had higher rates of vascular comorbidities than other patients with stroke. ED treat-and-release visits for a fall were significantly more common in the 15 days before stroke compared with the 15-day control period 1 year earlier (odds ratio, 2.7 [95% CI, 2.4-3.1]). The association between stroke and a preceding ED treat-and-release visit for a fall decreased in magnitude with increasing temporal distance from stroke.

conclusionsED treat-and-release visits for a fall are associated with significantly increased short-term ischemic stroke risk. These visits may be opportunities to improve stroke diagnostic accuracy and treatment in the ED.

Indexed as

Accidental FallsEmergency Service, HospitalAgedAged, 80 and overCross-Over StudiesFemaleHospitalizationHumansIschemic StrokeMaleMiddle AgedPatient DischargeRisk FactorsStrokedelayed diagnosisemergency services, hospitalInternational Classification of Diseasesischemic strokestroke

Identifiers

PMID38994584
PMCPMC11382293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.