Evidence map›Paper›PMID 38994537›Full record

ArticleBladder cancer (Amsterdam, Netherlands)2021

Significance and Mechanisms Analyses of

Dingguo Zhang, Jinjun Tian, Qier Xia, Zhenyu Yang, Bin Gu

Abstract read
In one paragraph

Article in Bladder cancer (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dingguo ZhangDepartment of Urology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Jinjun TianDepartment of Urology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Qier XiaDepartment of Urology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Zhenyu YangDepartment of Urology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Bin GuDepartment of Urology, Shanghai Pudong New Area People's Hospital, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBladder cancer is still a disease of significant morbidity and mortality. In bladder cancer,

methodsIn this study, we explored the Genomics of Drug Sensitivity in Cancer (GDSC) database for drug sensitivity. The latest TCGA data were downloaded for analysis. To deal with functional enrichment analysis, GSEA, KEGG and GO were used. Prognostic analyses have been carried out using the GEPIA online tool.

resultsResults from the GDSC database showed that bladder cancer cells with

conclusionsIn all, the significance of RB1 mutation in disease progression and drug selection in bladder cancer was suggested by our results, and multiple genes and pathways related to such a program were identified.

Indexed as

bioinformatics analysisBladder cancerdrug selectionRB1 mutationRNA sequencingTCGA

Identifiers

PMID38994537
PMCPMC11181786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.