Evidence map›Paper›PMID 38994400›Full record

ArticleChemical science2024

Quantifying Siglec-sialylated ligand interactions: a versatile

Unai Atxabal, Andrea Fernández, Maria Jesús Moure, Klaudia Sobczak, Corwin Nycholat, Verónica Almeida-Marrero, Iker Oyenarte, James C Paulson, Andrés de la Escosura, Tomás Torres and 3 more

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. JACS Au · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Perspectives on Applications ofMolecules (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Unai AtxabalChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.
Andrea FernándezChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.
Maria Jesús MoureChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.
Klaudia SobczakChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.
Corwin NycholatDepartments of Molecular Medicine and Immunology & Microbiology, The Scripps Research Institute 10550 North Torrey Pines Road La Jolla California 92037 USA.
Verónica Almeida-MarreroDepartment of Organic Chemistry, Universidad Autónoma de Madrid C/Francisco Tomás y Valiente 7 28049 Madrid Spain.
Iker OyenarteChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.
James C PaulsonDepartments of Molecular Medicine and Immunology & Microbiology, The Scripps Research Institute 10550 North Torrey Pines Road La Jolla California 92037 USA.
Andrés de la EscosuraDepartment of Organic Chemistry, Universidad Autónoma de Madrid C/Francisco Tomás y Valiente 7 28049 Madrid Spain.ORCID https://orcid.org/0000-0002-0928-8317
Tomás TorresDepartment of Organic Chemistry, Universidad Autónoma de Madrid C/Francisco Tomás y Valiente 7 28049 Madrid Spain.ORCID https://orcid.org/0000-0001-9335-6935
Niels C ReichardtGlycotechnology Laboratory, CIC biomaGUNE Paseo Miramon 194 San Sebastian 20014 Spain.ORCID https://orcid.org/0000-0002-9092-7023
Jesús Jiménez-BarberoChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.ORCID https://orcid.org/0000-0001-5421-8513
June Ereño-OrbeaChemical Glycobiology Lab, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) 48160 Derio Bizkaia Spain jjbarbero@cicbiogune.es jereno@cicbiogune.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialic-acid-binding immunoglobulin-like lectins (Siglecs) are integral cell surface proteins crucial for the regulation of immune responses and the maintenance of immune tolerance through interactions with sialic acids. Siglecs recognize sialic acid moieties, usually found at the end of

Identifiers

PMID38994400
PMCPMC11234860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.