Evidence map›Paper›PMID 38994350›Full record

ReviewFrontiers in immunology2024

Different origin-derived exosomes and their clinical advantages in cancer therapy.

Xiaoyan Jin, Jing Zhang, Yufu Zhang, Jing He, Mingming Wang, Yu Hei, Shutong Guo, Xiangrong Xu, Yusi Liu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  6. International journal of nanomedicine · 2026
    Article
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  9. Review
  10. Exosomes derived from umbilical cord blood NK cells inhibit the progression of pancreatic cancer by targeting ROS-mediated mitochondrial dysfunction.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoyan Jin *Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Jing Zhang *Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yufu Zhang *Department of Hepatobiliary Surgery, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Jing HeLaboratory of Obstetrics and Gynecology, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Mingming WangDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yu HeiDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Shutong GuoDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Xiangrong XuDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yusi LiuDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, as a class of small extracellular vesicles closely related to the biological behavior of various types of tumors, are currently attracting research attention in cancer diagnosis and treatment. Regarding cancer diagnosis, the stability of their membrane structure and their wide distribution in body fluids render exosomes promising biomarkers. It is expected that exosome-based liquid biopsy will become an important tool for tumor diagnosis in the future. For cancer treatment, exosomes, as the "golden communicators" between cells, can be designed to deliver different drugs, aiming to achieve low-toxicity and low-immunogenicity targeted delivery. Signaling pathways related to exosome contents can also be used for safer and more effective immunotherapy against tumors. Exosomes are derived from a wide range of sources, and exhibit different biological characteristics as well as clinical application advantages in different cancer therapies. In this review, we analyzed the main sources of exosomes that have great potential and broad prospects in cancer diagnosis and therapy. Moreover, we compared their therapeutic advantages, providing new ideas for the clinical application of exosomes.

Indexed as

Biomarkers, TumorExosomesNeoplasmsAnimalsHumansImmunotherapyLiquid BiopsyBiomarkers, Tumorbiomarkerscancer diagnosiscancer treatmentexosomestargeted delivery

Identifiers

PMID38994350
PMCPMC11236555

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.