ArticleTheranostics2024
Osteoblast-specific down-regulation of NLRP3 inflammasome by aptamer-functionalized liposome nanoparticles improves bone quality in postmenopausal osteoporosis rats.
Abstract read
In one paragraph
Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From mechanisms to therapeutics: a narrative review on pyroptosis and autophagy in osteoporosis.Annals of medicine · 2025Pooled it
- Macrophage metabolic reprogramming via HIF-1α-glycolysis drives osteoblast ferroptosis and bone loss through an IL-6-STAT3-dependent redox axis.Redox report : communications in free radical research · 2026Article
- Surface-Engineered Phytochemical Nanomedicines for Postmenopausal Osteoporosis: Skeletal Targeting, Imaging-Supported Evaluation, and Therapeutic Performance.Pharmaceutics · 2026Review
- Hesperetin mitigates IBD-associated bone loss viaJournal of orthopaedic translation · 2026Article
- Macrophage immunometabolic reprogramming in inflammatory repair failure in osteonecrosis of the femoral head.Journal of orthopaedic translation · 2026Review
- A Decoy-Receptor-Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- HypervirulentMicrobiology spectrum · 2026Article
- Cellular signaling crosstalk between osteoporosis and diabetes: Common mechanisms and therapeutic targets (Review).Biomedical reports · 2026Review
- From sugar to flames: the detrimental role of pyroptosis in diabetes-associated bone loss.Molecular biology reports · 2026Review
- Liposomal multimodal theranostics for bone disorders: from rational responsive delivery and biomimetic strategies to clinical translation.Journal of nanobiotechnology · 2026Review
- Lipid nanoparticles for nucleic acid delivery to osteoblasts and osteoblast-lineage cells: A systematic review.Bone reports · 2026Review
- Decoding Undesirable Inflammatory Responses of Nucleic Acid-Delivering Lipid Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Aptamer-Functionalized Nanocarriers for Bone and Joint Diseases: Engineering Design Rules and Translational Roadmap.Small science · 2026Article
- Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review).International journal of molecular medicine · 2026Review
- Raman spectroscopic fingerprinting uncovers a multi-scale structural-mechanical-transcriptomic coupling landscape in osteoporosis.Frontiers in endocrinology · 2026Article
- Aptamers in Osteoimmune Regulation: Scientific Rationale, Emerging Evidence and Translational Challenges.International journal of nanomedicine · 2026Review
- Osteoimmune senescence in aging-related bone diseases.Frontiers in immunology · 2026Review
- Regulation of osteoclastogenesis and bone resorption by fatty acid metabolism: mechanisms and therapeutic opportunities.Frontiers in endocrinology · 2026Review
- Insights Into the HIF-1α-Mediated NLRP3 Pyroptosis Pathway in the Regulation of Musculoskeletal Diseases in the High-Altitude Environment.Journal of inflammation research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Lijun XuDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jie ZhuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Lingjun RongDepartment of Geriatric Endocrinology, the First Affiliated Hospital of Zheng Zhou University, Zhengzhou 450052, China.
Huinan YangState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Bin WangState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Shuai LuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Lingxiao ZhangKey Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Fuyi LiDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Shihua YangDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhifang WangDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Chong LiDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xiao HuCollege of Life Science, Capital Normal University, Haidian District, Beijing 100048, China.
Ruoyun LiuSchool of Biomedicine, Beijing City University, Beijing 100094, China.
Lili ZhengDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Hongjian LiuDepartment of Orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Haohao ZhangDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Yanling LiuDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Di ZhaoDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Shuiying ZhaoDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Lun ZhangState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Yingbo JiaState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Shiyu LiangState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Zhikang GuoDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xixiu XieState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Ruitian LiuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Lixia ZhangDepartment of Endocrinology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
InflammasomesLiposomesNanoparticlesNLR Family, Pyrin Domain-Containing 3 ProteinOsteoblastsOsteoporosis, PostmenopausalAnimalsAptamers, NucleotideDisease Models, AnimalDown-RegulationFemaleHumansMiddle AgedOvariectomyRatsRats, Sprague-DawleyAptamers, NucleotideInflammasomesLiposomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanNlrp3 protein, ratRNA, Small Interferingdiagnosislipid nanoparticlesNLRP3 inflammasomeosteoblast-specific aptamerpostmenopausal osteoporosis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.