ReviewFrontiers in transplantation2023
Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost.
Review in Frontiers in transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- A randomized, controlled, double-blinded trial on the effects of acellular dermal matrices on the functional assessment and qualitative satisfaction of split-thickness skin grafts.Scientific reports · 2025Trial
- Combined anterior latissimus dorsi and teres major tendon transfer with tuberoplasty using acellular dermal matrix for anterosuperior irreparable rotator cuff tears: a technical note.JSES reviews, reports, and techniques · 2026Article
- The use of porcine acellular dermal matrices in implant-based breast reconstruction: A systematic literature review.JPRAS open · 2026Review
- Biomimetic Dermal Substitutes for Skin Reconstruction: Advances in Scaffold Design, Biological Integration, and Clinical Performance.Journal of functional biomaterials · 2026Review
- Early Biocompatibility of Brown Macroalgal Scaffolds in a Splinted Full-Thickness Rodent Wound Model: A Pilot Study.Journal of functional biomaterials · 2026Article
- Prospective Observational Study of Supercritical Carbon Dioxide-Processed Acellular Dermal Matrix in Implant-Based Breast Reconstruction.Archives of plastic surgery · 2026Article
- Evaluating Rectus Abdominis Fascia and Alloderm as Wrapping Materials in Diced Cartilage Grafts for Dorsal Nasal Augmentation.Aesthetic plastic surgery · 2026Article
- How to approach the deep inferior epigastric perforator flap revision for optimal aesthetics.Gland surgery · 2026Review
- Host Biologic Response to Acellular Dermal Matrices of Human and Porcine Origin.Aesthetic surgery journal. Open forum · 2026Article
- Bovine Dermal Collagen Matrix for Early Graft Readiness in a Full-Thickness Posterior Neck Burn: A Case Report.Cureus · 2025Article
- Immunogenicity and Integration of a Decellularized Extracellular Matrix-Based Scaffold for the Reconstruction of Human Foreskin: A Preclinical Animal Study.Bioengineering (Basel, Switzerland) · 2025Article
- Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care.International wound journal · 2025Article
- Chest Wall Reconstruction Using Titanium Mesh With Fortiva Acellular Dermal Matrix Sandwich Technique.Annals of thoracic surgery short reports · 2025Article
- Direct-to-Implant Prepectoral Breast Reconstruction with a Novel Collagen Matrix Following Nipple-Sparing Mastectomy: A Case Report.Reports (MDPI) · 2025Article
- Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix-free, Direct-to-implant Hybrid Reconstruction.Plastic and reconstructive surgery. Global open · 2025Article
- Article
- Inferior Breast Pole Dermal Flap: A 7-year Experience.Plastic and reconstructive surgery. Global open · 2025Article
- Biologic Response With and Without Acellular Dermal Matrix in Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2025Article
- Article
- The safety and anti-adhesive effect of acellular dermal matrix application after thyroid surgery: a multicenter randomized controlled trial.Annals of surgical treatment and research · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern tissue engineering has made substantial advancements that have revolutionized plastic surgery. Acellular dermal matrix (ADM) is an example that has gained considerable attention recently. ADM can be made from humans, bovines, or porcine tissues. ADM acts as a scaffold that incorporates into the recipient tissue. It is gradually infiltrated by fibroblasts and vascularized. Fortunately, many techniques have been used to remove cellular and antigenic components from ADM to minimize immune system rejection. ADM is made of collagen, fibronectin, elastin, laminin, glycosaminoglycans, and hyaluronic acid. It is used in critical wounds (e.g., diabetic wounds) to protect soft tissue and accelerate wound healing. It is also used in implant-based breast reconstruction surgery to improve aesthetic outcomes and reduce capsule contracture risk. ADM has also gained attention in abdominal and chest wall defects. Some studies have shown that ADM is associated with less erosion and infection in abdominal hernias than synthetic meshes. However, its higher cost prevents it from being commonly used in hernia repair. Also, using ADM in tendon repair (e.g., Achilles tendon) has been associated with increased stability and reduced rejection rate. Despite its advantages, ADM might result in complications such as hematoma, seroma, necrosis, and infection. Moreover, ADM is expensive, making it an unsuitable option for many patients. Finally, the literature on ADM is insufficient, and more research on the results of ADM usage in surgeries is needed. This article aims to review the literature regarding the application, Benefits, and costs of ADM in reconstructive surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.