Evidence map›Paper›PMID 38993775›Full record

ArticleFrontiers in transplantation2024

The association between body mass index, exercise capacity, and health-related quality of life in heart transplant recipients.

Margrethe Flesvig Holt, Stine Holmen, Katrine Rolid, Kristine V Brautaset Englund, Charlotte M Østby, Håvard Ravnestad, Arne K Andreassen, Lars Gullestad, Einar Gude, Kaspar Broch

Abstract read
In one paragraph

Article in Frontiers in transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitors in Heart Transplant Recipients: A Systematic Review and Meta-analyses.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Margrethe Flesvig HoltDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Stine HolmenDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Katrine RolidDepartment of Health and Public Sector, The Research Council of Norway, Oslo, Norway.
Kristine V Brautaset EnglundDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Charlotte M ØstbyDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Håvard RavnestadDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Arne K AndreassenDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Lars GullestadDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Einar GudeDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Kaspar BrochDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Pre-transplant obesity and weight gain after heart transplantation are both associated with increased risk of poor clinical outcomes. We aimed to assess the association between overweight or obesity, exercise capacity, and health-related quality of life in heart transplant recipients. Methods: This study is based on baseline data from the IronIC trial, in which we randomized 102 heart transplant recipients with iron deficiency to ferric derisomaltose or placebo. We performed cardio pulmonary exercise testing in all participants. To assess quality of life, we used the SF-36v2 questionnaire, using two sum scores: the physical component summary and the mental component summary. A minimal clinically important difference was defined as ≥2 and ≥3 for the physical and the mental component summary, respectively. Results: 24/102 heart transplant recipients (24%) had a body mass index (BMI) ≥30 kg/m Conclusion: Almost a quarter of our heart transplant recipients in long-term follow-up had a BMI ≥30 kg/m

Indexed as

heart transplantation (HTx)heart transplant recipientHRQoL (health-related quality of life)obesityoxygen consumption (VO2peak)

Identifiers

PMID38993775
PMCPMC11235288

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.