ArticleiScience2024
A neutral invertase controls cell division besides hydrolysis of sucrose for nutrition during germination and seed setting in rice.
Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Elevated COProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Duet between sugars and hormones: The molecular dialogue fine-tuning hypoxia acclimation in plants.Journal of integrative plant biology · 2026Review
- Article
- Mango Fructokinases Inhibit Sugar Accumulation and Enhance Energy Metabolism in Transgenic Tomato.Plants (Basel, Switzerland) · 2025Article
- Comprehensive Evaluation of Biogas Slurry Fertility: A Study Based on the Effects of Biogas Slurry Irrigation on Soil Microorganisms and Enzyme Activities in Winter Wheat Fields.Microorganisms · 2025Article
- Genome-wide identification of invertase genes in sweetpotato and its response to nitrogen and planting densities.BMC plant biology · 2025Article
- OsFKBP12 transduces the sucrose signal from OsNIN8 to the OsTOR pathway in a loosely binding manner for cell division.iScience · 2025Article
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3 authors.
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Abstract
Sucrose is the transport form of carbohydrate in plants serving as signal molecule besides nutrition, but the signaling is elusive. Here, neutral invertase 8 (OsNIN8) mutated at G461R into OsNIN8m, which increased its charge and hydrophobicity, decreased hydrolysis of sucrose to 13% and firmer binding to sucrose than the wildtype. This caused downstream metabolites and energy accumulation forming overnutrition. Paradoxically, division of subinitials in longitudinal cell lineages was only about 15 times but more than 100 times in wildtype, resulting in short radicle. Further, mutation of OsNIN8 into deficiency of hydrolysis but maintenance of sucrose binding allowed cell division until ran out of energy showing the association but not hydrolysis gave the signal. Chemically, sucrose binding to OsNIN8 was exothermic but to OsNIN8m was endothermic. Therefore, OsNIN8m lost the signal function owing to change of thermodynamic state. So, OsNIN8 sensed sucrose for cell division besides hydrolyzed sucrose.
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