Evidence map›Paper›PMID 38993570›Full record

ArticleInternational journal of biological sciences2024

ETS1-mediated Regulation of SOAT1 Enhances the Malignant Phenotype of Oral Squamous Cell Carcinoma and Induces Tumor-associated Macrophages M2-like Polarization.

Yueying Liu, Li Shen, Yi Li, Xiaoyan Sun, Lu Liang, Shiyao Jiang, Ziyun Zhang, Xingjie Tang, Yongguang Tao, Li Xie and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. [p53-SOAT1 Axis: A Novel Target for Tumor Lipid Metabolism and Therapy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
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  14. Article
  15. Article
  16. Effects of macrophages in OSCC progression.Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yueying LiuThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Li ShenThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Yi LiThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Xiaoyan SunThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Lu LiangThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Shiyao JiangThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Ziyun ZhangThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Xingjie TangThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Yongguang TaoDepartment of Pathology, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Xiangya Hospital, School of Basic Medicine, Central South University, Changsha, 410013 Hunan, China.
Li XieDepartment of Head and Neck Surgery, Hunan Cancer Hospital, Xiangya School of Medicine, Central South University, Changsha, 410013 Hunan, China.
Yiqun JiangThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.
Li CongThe Key Laboratory of Model Animal and Stem Cell Biology in Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013 Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is an aggressive cancer that poses a substantial threat to human life and quality of life globally. Lipid metabolism reprogramming significantly influences tumor development, affecting not only tumor cells but also tumor-associated macrophages (TAMs) infiltration.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsProto-Oncogene Protein c-ets-1Tumor-Associated MacrophagesAnimalsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansMaleMiceETS1 protein, humanProto-Oncogene Protein c-ets-1ETS1Immune infiltrationM2-like polarizationOral squamous cell carcinomaSOAT1Tumor associated macrophages

Identifiers

PMID38993570
PMCPMC11234219

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.