Evidence map›Paper›PMID 38993425›Full record

ArticleCureus2024

Falling From Laughing: Laughing Gas-Induced Subacute Combined Degeneration From Nitrous Oxide.

Abhinav K Rao, Fahim Syed, Thomas J Lee, Gilberto U Umanzor, Jeffrey Bodle

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abhinav K RaoInternal Medicine, Trident Medical Center, Charleston, USA.
Fahim SyedInternal Medicine, Trident Medical Center, Charleston, USA.
Thomas J LeeInternal Medicine, Rutgers University New Jersey Medical School, Newark, USA.
Gilberto U UmanzorInternal Medicine, Trident Medical Center, Charleston, USA.
Jeffrey BodleNeurology, Trident Medical Center, Charleston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laughing gas is becoming increasingly popular as a recreational drug of choice, particularly among young adults. Nitrous oxide, the toxic component of laughing gas, can cause neuronal injury when used in high doses. Through multiple mechanisms, nitrous oxide leads to B12 depletion and subsequent demyelination, particularly in the spinal cord. Here, we present the case of a 27-year-old female who presented with ataxia and was found to have laughing gas-induced subacute combined degeneration from nitrous oxide. After aggressive vitamin B12 repletion and laughing gas cessation for three months, the patient improved.

Indexed as

laughing gasneurologynitrous oxidenitrous oxide abusesubacute combined degeneration

Identifiers

PMID38993425
PMCPMC11238261

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.