Evidence map›Paper›PMID 38993249›Full record

ArticleWorld journal of oncology2024

Hereditary Gastric Cancer Is Linked With Hereditary Breast and Ovarian Cancer.

Takuma Hayashi, Kenji Sano, Mako Okada, Takashi Ura, Ikuo Konishi

Abstract read
In one paragraph

Article in World journal of oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takuma HayashiCancer Medicine, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.
Kenji SanoPathological Division, Shinshu University Hospital, Matsumoto, , Nagano 390-0877, Japan.
Mako OkadaCancer Medicine, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.
Takashi UraMedical Oncology, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.
Ikuo KonishiCancer Medicine, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We retrospectively reviewed data from Japanese patients undergoing precision treatment using cancer genomic medicine. Results: We found a higher GC incidence in HBOC families having germline pathogenic variants (GPVs) of Conclusion: Our study highlights the need to investigate the potential of therapeutic agents against BRCA1/2 PVs to avoid the development of GC in HBOC families. In addition, our results suggest that poly (ADP-ribose) polymerase (PARP) inhibitors could potentially inhibit GC development and progression with gBRCA1/2 PVs.

Indexed as

BRCA1BRCA2Gastric cancerHBOCHelicobacter pylori

Identifiers

PMID38993249
PMCPMC11236378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.