Evidence map›Paper›PMID 38992859›Full record

ArticleAmerican journal of epidemiology2025

The effect of youth-friendly health services on risk of pregnancy among adolescent girls and young women in Lilongwe, Malawi: a secondary analysis of the Girl Power-Malawi study.

Lauren A Graybill, Daniel Westreich, Bertha Maseko, Twambilile Phanga, Tiyamike Nthani, Dhrutika Vansia, Benjamin H Chi, Julie L Daniels, Jennifer H Tang, Linda-Gail Bekker and 2 more

Abstract readMulticenter Study
In one paragraph

Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren A GraybillInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0002-8679-642X
Daniel WestreichDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0003-3069-1650
Bertha MasekoClinical Research Programme, Malawi-Liverpool-Wellcome Trust, Blantyre 312225, Malawi.
Twambilile PhangaUNC Project-Malawi, University of North Carolina at Chapel Hill, Lilongwe 207233, Malawi.
Tiyamike NthaniUNC Project-Malawi, University of North Carolina at Chapel Hill, Lilongwe 207233, Malawi.
Dhrutika VansiaUNC Project-Malawi, University of North Carolina at Chapel Hill, Lilongwe 207233, Malawi.
Benjamin H ChiDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0002-1435-8455
Julie L DanielsDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Jennifer H TangDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Linda-Gail BekkerDesmond Tutu HIV Centre, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0002-0755-4386
Audrey E PettiforDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0002-3387-0817
Nora E RosenbergDepartment of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0002-9759-9966

Funding

Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
A dyad approach to combination HIV prevention in pregnancy for Zambia and MalawiR01AI131060 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H., MUTALE, WILBROAD · 2017 to 2020
$2.7M
Mentoring new investigators in PMTCT implementation researchK24AI120796 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Benjamin H. Chi · 2016 to 2026
$1.3M
Developing a risk assessment tool to identify HIV-uninfected adolescent girls and young women at highest risk for HIV infection: a key step for targeted biomedical HIV preventionR21MH125705 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2021 to 2022
$428k
Evidence for HIV Prevention in Southern AfricaNational Institute of Allergy and Infectious Diseases at the National Institutes of Health R01AI131060National Institute of Mental Health at the National Institutes of Health R21MH125705NIAID NIH HHS K24 AI120796NIAID NIH HHS R01 AI131060NIAID NIH HHS T32 AI007001NIMH NIH HHS R21 MH125705
6 · The paper itself

Abstract

In sub-Saharan Africa, adolescent girls and young women aged 15 to 24 (AGYW) experience a high risk of early and unintended pregnancy. We assessed the impact of youth-friendly health services (YFHS) on pregnancy risk among AGYW who participated in the Girl Power study. In 2016, Girl Power randomly assigned 4 government-run health centers in Lilongwe, Malawi, to provide a standard (n = 1) or youth-friendly (n = 3) model of service delivery. At 6 and 12 months, study participants (n = 250 at each health center) self-reported their current pregnancy status and received a urine pregnancy test. Because of missing pregnancy test results, we used multiple imputation to correct for outcome misclassification in self-reported pregnancy status and applied the parametric g-formula on the corrected data to estimate the effect of YFHS on the 12-month risk of pregnancy. After correcting for outcome misclassification, the risk of pregnancy under the scenario where all health centers offered YFHS was 15.8% compared to 23.2% under the scenario where all health centers offered standard of care (risk difference: -7.3%; 95% CI, -15.5% to 0.8%). Access to a model of YFHS that integrates provider training with youth-friendly clinic modifications and community outreach activities may decrease risk of pregnancy among AGYW relative to standard of care.

Indexed as

Pregnancy in AdolescenceAdolescentFemaleHumansMalawiPregnancyPregnancy, UnplannedRandom AllocationYoung Adulthealth servicespregnancySub-Saharan Africayoung people

Identifiers

PMID38992859
PMCPMC13368593

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.