ArticleActa veterinaria Scandinavica2024
Effect of surgery on oxidative stress and endogenous tocopherol concentrations in juvenile female dogs.
Article in Acta veterinaria Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Brown Macroalgal Polyphenols and Oxidative Stress: A Systematic Review and Meta-Analysis of In Vivo Evidence in Vertebrate Models.Antioxidants (Basel, Switzerland) · 2026Review
- Comparison of analgesic efficacy between intrafunicular and intratesticular lidocaine injection in dogs.Frontiers in veterinary science · 2026Article
- Assessment of Pain, Vital Parameters and Oxidative Stress Markers in Dogs After Celiotomy and Three-Port Laparoscopic Ovariectomy.Veterinary medicine and science · 2025Article
- Impact of Two Surgical Techniques for Umbilical Hernia Repair, With and Without Peritoneal Opening, on Pain Response, Sedation, and Oxidative Stress in Calves.Veterinary sciences · 2025Article
- Ovariectomy in Canine Surgical Medicine: A Comparative Analysis of Surgical Approaches and the Nociceptive, Inflammatory, and Oxidative Stress Responses.Animals : an open access journal from MDPI · 2025Article
- Evaluation of Depth of Anesthesia Sleep Quality in Swine Undergoing Hernia Repair: Effects of Romifidine/Ketamine-Diazepam Protocols with and Without Tramadol and the Potential Role of Serotonin as a Biomarker.Veterinary sciences · 2025Article
- Assessment of Oxidative Stress Markers in Cats Undergoing Ovariohysterectomy by a Midline or Flank Approach.Veterinary medicine and science · 2025Article
- Expression of AMPK and PLIN2 in the regulation of lipid metabolism and oxidative stress in bitches with open cervix pyometra.BMC veterinary research · 2025Article
- Impact of Ovarian Suspensory Ligament Rupture on Surgical Stress in Elective Ovariohysterectomy in Bitches.Veterinary sciences · 2024Article
- Analgesic efficacy of tapentadol in chronic joint disorders in horses: plasma serotonin concentration and adrenocortical response as biomarkers of pain-induced stress.Frontiers in veterinary science · 2024Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundSurgery such as ovariectomy causes an inflammatory and oxidative stress. This study was designed to evaluate endogenous tocopherol levels in response to surgical oxidative stress induced by abdominal surgery (ovariectomy) in thirty-two juvenile female dogs. The dogs received meloxicam before surgery (0.2 mg/kg SC) and after surgery (0.1 mg/kg OS every 24 h), 0.03 mg/kg of atropine sulfate (IM), and propofol 4 mg/kg intravenously (IV). General anesthesia was maintained with sevoflurane. Physiological, hematological and biochemical parameters, malondialdehyde (MDA) and α-, δ-, γ-tocopherols were evaluated at baseline, 36 and 48 h after surgery.
resultsThe physiological parameters remained within normal ranges. Blood glucose concentration increased, while the albumin levels decreased after surgery. Rescue analgesia was not required. MDA levels increased above the baseline at 36 and 48 h after surgery (P < 0.001). The α-, δ-, and γ-tocopherol concentrations decreased from baseline at 36 and 48 h after surgery (P < 0.001).
conclusionsSurgery in juvenile female dogs revealed oxidative, increased MDA concentrations, reduced tocopherol levels, and had a clinically insignificant influence on homeostasis.
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