Evidence map›Paper›PMID 38992088›Full record

ArticleScientific reports2024

An optical photothermal infrared investigation of lymph nodal metastases of oral squamous cell carcinoma.

Safaa Al Jedani, Cassio Lima, Caroline I Smith, Philip J Gunning, Richard J Shaw, Steve D Barrett, Asterios Triantafyllou, Janet M Risk, Royston Goodacre, Peter Weightman

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The CHI3L1 protein plays role as a protecting factor against autophagy in glioblastoma cells.Apoptosis : an international journal on programmed cell death · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Safaa Al JedaniDepartment of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK.
Cassio LimaCentre for Metabolomics Research, Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.
Caroline I SmithDepartment of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK.
Philip J GunningDepartment of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK.
Richard J ShawDepartment of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK.
Steve D BarrettDepartment of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK.
Asterios TriantafyllouDepartment of Cellular Pathology, Liverpool Clinical Laboratories, University of Liverpool, Liverpool, L7 8YE, UK.
Janet M RiskDepartment of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK.
Royston GoodacreCentre for Metabolomics Research, Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.
Peter WeightmanDepartment of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK. peterw@liverpool.ac.uk.

Funding

Cancer Research UK 26196Cancer Research UK C7738/A26196EPSRC SFI EP/V042882/1
6 · The paper itself

Abstract

In this study, optical photothermal infrared (O-PTIR) spectroscopy combined with machine learning algorithms were used to evaluate 46 tissue cores of surgically resected cervical lymph nodes, some of which harboured oral squamous cell carcinoma nodal metastasis. The ratios obtained between O-PTIR chemical images at 1252 cm

Indexed as

Carcinoma, Squamous CellLymphatic MetastasisMouth NeoplasmsFemaleHumansLymph NodesMachine LearningMaleNeural Networks, ComputerROC CurveSpectrophotometry, Infrared

Identifiers

PMID38992088
PMCPMC11239877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.