SynthesisScientific reports2024
Multimodal prehabilitation and postoperative outcomes in upper abdominal surgery: systematic review and meta-analysis.
Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07700459 (A Randomised-controlled Trial to Assess the Impact of Prehabilitation and a Structured Exercise Programme on Cardiorespiratory Performance in Adults Awaiting Elective Surgery for Congenital Heart Disease), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised-controlled Trial to Assess the Impact of Prehabilitation and a Structured Exercise Programme on Cardiorespiratory Performance in Adults Awaiting Elective Surgery for Congenital Heart Disease: The ACE-CHD Trial.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Integrating multimodal prehabilitation into enhanced recovery after surgery programs (MPhERAS) for elderly patients: a systematic review and meta-analysis of randomized controlled trials and cohort studies.Techniques in coloproctology · 2025Pooled it
- ASO Author Reflections: Multi-Modal Prehabilitation and Outcomes After Gastroesophageal Cancer Surgery: A Cohort Study of Pulmonary Complications and Resilience to Major Postoperative Events.Annals of surgical oncology · 2026Article
- Thoracic Epidural Analgesia in Major Cancer Surgery: An Update.Medicina (Kaunas, Lithuania) · 2026Review
- Frailty and sarcopenia proxies are associated with postoperative outcomes after abdominal wall reconstruction: a national database analysis.Surgical endoscopy · 2026Article
- Exploring barriers to care and patient perspectives in metabolic and bariatric surgery.Surgical endoscopy · 2026Article
- Preoperative physical exercise training for people scheduled for major abdominal surgery.The Cochrane database of systematic reviews · 2026Article
- Effects of prehabilitation on outcomes among patients undergoing surgery for lung cancer: a systematic review and meta-analysis of randomized controlled trials.Journal of thoracic disease · 2026Article
- Prehabilitation and postoperative outcomes in colorectal surgery: an umbrella review.Journal of anesthesia, analgesia and critical care · 2026Review
- Preoperative prehabilitation in adults: A concept analysis.International journal of nursing studies advances · 2026Review
- Effects of surgery on cancer metastasis: biological mechanisms and perioperative implications.Frontiers in oncology · 2026Review
- Impact of a multimodal prehabilitation program on postoperative recovery in patients undergoing total laparoscopic hysterectomy and its clinical effects on reducing the risk of venous thromboembolism occurrence.Frontiers in oncology · 2026Article
- Physical activity and systemic treatment outcomes in advanced thyroid cancer.Endocrine oncology (Bristol, England) · 2026Article
- Preoperative Anesthesia Assessment in Elderly Patients: Challenges and Opportunities for Safer Perioperative Care.Cureus · 2025Review
- Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts.World journal of gastrointestinal surgery · 2025Article
- Revisiting anesthesia-induced preconditioning for neuroprotection in the aging brain: a narrative review.Korean journal of anesthesiology · 2025Review
- Kinesiological insights into exercise prescription within oncological prehabilitation: current knowledge and future perspectives.Frontiers in sports and active living · 2025Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The impact of multimodal prehabilitation on postoperative complications in upper abdominal surgeries is understudied. This review analyzes randomized trials on multimodal prehabilitation with patient and hospital outcomes. MEDLINE, Embase, CINAHL, and Cochrane CENTRAL were searched for trials on prehabilitation before elective (non-emergency) abdominal surgery. Two reviewers independently screened studies, extracted data, and assessed study quality. Primary outcomes of interest were postoperative pulmonary complications (PPCs) and all-cause complications; secondary outcomes included hospital and intensive care length of stay. A meta-analysis with random-effect models was performed, and heterogeneity was evaluated with I-square and Cochran's Q test. Dichotomous variables were reported in log-odds ratio and continuous variables were presented as mean difference. Ten studies (total 1503 patients) were included. Odds of developing complications after prehabilitation were significantly lower compared to various control groups (- 0.38 [- 0.75- - 0.004], P = 0.048). Five studies described PPCs, and participants with prehabilitation had decreased odds of PPC (- 0.96 [- 1.38- - 0.54], P < 0.001). Prehabilitation did not significantly reduce length of stay, unless exercise was implemented; with exercise, hospital stay decreased significantly (- 0.91 [- 1.67- - 0.14], P = 0.02). Multimodal prehabilitation may decrease complications in upper abdominal surgery, but not necessarily length of stay; research should address heterogeneity in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.