Evidence map›Paper›PMID 38992012›Full record

ArticleScientific data2024

Histopathology imaging and clinical data including remission status in pediatric inflammatory bowel disease.

Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic and 3 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chloe Martin-KingResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA. chloe.martin.king@choc.org.ORCID 0000-0002-8276-4965
Ali NaelDepartment of Pathology, CHOC, Orange, CA, USA.
Louis EhwerhemuephaResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.ORCID 0000-0003-1369-7954
Blake CalvoResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.
Quinn GatesResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.
Jamie JanchoiResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.
Elisa OrnelasResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.
Melissa PerezDepartment of Gastroenterology and Nutrition, CHOC, Orange, CA, USA.
Andrea VenderbyResearch Institute, Children's Health Orange County (CHOC), Orange, CA, USA.
John MiklavcicSchmid College of Science and Technology, Chapman University, Orange, CA, USA.
Peter ChangCenter for Artificial Intelligence in Diagnostic Medicine (CAIDM), UCI, Irvine, CA, USA.
Aaron SassoonDepartment of Pathology, CHOC, Orange, CA, USA.
Kenneth GrantDepartment of Gastroenterology and Nutrition, CHOC, Orange, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of inflammatory bowel disease (IBD) is increasing annually. Children with IBD often suffer significant morbidity due to physical and emotional effects of the disease and treatment. Corticosteroids, often a component of therapy, carry undesirable side effects with long term use. Steroid-free remission has become a standard for care-quality improvement. Anticipating therapeutic outcomes is difficult, with treatments often leveraged in a trial-and-error fashion. Artificial intelligence (AI) has demonstrated success in medical imaging classification tasks. Predicting patients who will attain remission will help inform treatment decisions. The provided dataset comprises 951 tissue section scans (167 whole-slides) obtained from 18 pediatric IBD patients. Patient level structured data include IBD diagnosis, 12- and 52-week steroid use and name, and remission status. Each slide is labelled with biopsy site and normal or abnormal classification per the surgical pathology report. Each tissue section scan from an abnormal slide is further classified by an experienced pathologist. Researchers utilizing this dataset may select from the provided outcomes or add labels and annotations from their own institutions.

Indexed as

Inflammatory Bowel DiseasesAdolescentArtificial IntelligenceChildHumansRemission Induction

Identifiers

PMID38992012
PMCPMC11239805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.