Evidence map›Paper›PMID 38991842›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2024

Quality of life improvement from thoracoscopic atrial fibrillation ablation in women versus men: a prospective cohort study.

Lara M Vos, Rein Vos, Pythia T Nieuwkerk, Peter-Paul W K Vos, Frederik N Hofman, Robert J M Klautz, Bart P Van Putte

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lara M VosDepartment of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-3510-665X
Rein VosDepartment of Methodology and Statistics, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center, Maastricht, the Netherlands.
Pythia T NieuwkerkDepartment of Medical Psychology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Peter-Paul W K VosDepartment of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, the Netherlands.
Frederik N HofmanDepartment of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, the Netherlands.
Robert J M KlautzDepartment of Cardiothoracic Surgery, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Bart P Van PutteDepartment of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, the Netherlands.

Funding

AtriCure
6 · The paper itself

Abstract

objectivesThoracoscopic ablation has proven to be an effective and safe rhythm control strategy, especially for persistent atrial fibrillation. However, its impact on quality of life (QoL) and potential gender differences remains unclear.

methodsThis prospective, single-centre observational study included consecutive patients with symptomatic atrial fibrillation undergoing thoracoscopic ablation. QoL was measured using the Short Form 36 (SF-36) and Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaires and longitudinal trend analysis including linear mixed models was used to assess gender-specific differences.

resultsA total of 191 patients were included; mean age 63.9 ± 8.6 years, 61 (31.9%) women and 148 (77.5%) with non-paroxysmal atrial fibrillation. Women were older, more symptomatic and reported lower baseline QoL. AFEQT summary scores substantially improved after three months (relative increase 51.5% from baseline; P < 0.001) and persisted up to 1-year (57.2%; P < 0.001). Women showed substantial QoL improvement, which was comparable to men at 1 year. Distinct gender-related trajectories for AFEQT were observed. Women showed more often clinically important decline over time, yet AF recurrence and age were predictive factors in both men and women. Patients with AF recurrence also experienced QoL improvements, albeit to a lesser extent than those in sinus rhythm (61.3% vs 26.9%, P < 0.001), with no differences between men and women.

conclusionsThoracoscopic ablation for atrial fibrillation results in substantial QoL improvement and was comparable for men and women. Understanding sex-specific and age-related trajectories is important to further enhance patient-centred atrial fibrillation care.

Indexed as

AblationAtrial fibrillationGenderQuality of lifeSurgicalThoracoscopic

Identifiers

PMID38991842
PMCPMC11268440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.