Evidence map›Paper›PMID 38991671›Full record

ArticleBMJ open2024

Barriers and facilitators of habit building for long-term adherence to antihypertensive therapy among people with hypertensive disorders in Los Angeles, California: a qualitative study.

Ishita Ghai, Alina Palimaru, Joseph E Ebinger, Denisse Barajas, Rocio Vallejo, Michelle Morales, Sebastian Linnemayr

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04029883 (Behavioral Economics to Improve Antihypertensive Therapy Adherence), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04029883 nacompletednot on this map

Behavioral Economics to Improve Antihypertensive Therapy Adherence (BETA)

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2022 to 2024Enrolled60ConditionsHypertension, Medication AdherenceArmsText Message, Behavior Economic Incentive
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ishita GhaiPardee RAND Graduate School, Santa Monica, California, USA ighai@pardeerand.edu.ORCID 0000-0002-7112-257X
Alina PalimaruRAND Corporation, Santa Monica, California, USA.
Joseph E EbingerSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Denisse BarajasSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Rocio VallejoSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Michelle MoralesSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sebastian LinnemayrRAND Corporation, Santa Monica, California, USA.

Funding

Behavioral Economics to improve Antihypertensive Therapy Adherence (BETA)R21HL156132 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI EBINGER, JOSEPH, LINNEMAYR, SEBASTIAN · 2021 to 2022
$506k
NHLBI NIH HHS R21 HL156132
6 · The paper itself

Abstract

objectivesThe aim of this study was to a) explore barriers and facilitators associated with medication-taking habit formation, and b) elicit feedback on the components of an intervention designed to help form strong habits for long-term medication adherence.

designThe study design was qualitative; we conducted semistructured interviews between September 2021 and February 2022.

settingThe interviews were conducted online, with 27 participants recruited at the Cedars-Sinai Medical Center in Los Angeles, California.

participantsA purposive sample of 20 patients who were over 18 years of age, had been diagnosed with hypertensive disorder (or reported high blood pressure; >140/90 mm Hg) and who were prescribed antihypertensive therapy at the time of recruitment, along with seven providers were interviewed.

resultsContextual factors included frequent changes to prescription for regimen adjustment, and polypharmacy. Forgetfulness, perceived need for medication, and routine disruptions were identified as possible barriers to habit formation. Facilitators of habit formation included identification of stable routines for anchoring, planning, use of external reminders (including visual reminders) and pillboxes for prescription management, and extrinsic motivation for forming habits. Interestingly, experiencing medication side effects was identified as a possible barrier and a possible facilitator of habit formation. Feedback on study components included increasing text size, and visual appeal of the habit leaflet; and imparting variation in text message content and adjusting their frequency to once a day. Patients generally favoured the use of conditional financial incentives to support habit formation.

conclusionThe study sheds light on some key considerations concerning the contextual factors for habit formation among people with hypertension. As such, future studies may evaluate the generalisability of our findings, consider the role of visual reminders in habit formation and sustenance, and explore possible disruptions to habits. TRIAL REGISTRATION NUMBER: NCT04029883.

Indexed as

Antihypertensive AgentsDrug MonitoringHypertensionQualitative ResearchAdultAgedFemaleHabitsHumansInterviews as TopicLos AngelesMaleMiddle AgedMotivationReminder SystemsAntihypertensive Agentsbehaviorcardiologyhypertensionqualitative research

Identifiers

PMID38991671
PMCPMC11243207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.