Evidence map›Paper›PMID 38991220›Full record

ArticleJournal of the American Chemical Society2024

Dynamic Second Harmonic Imaging of Proton Translocation Through Water Needles in Lipid Membranes.

Seonwoo Lee, Chetan S Poojari, Anna Maznichenko, David Roesel, Iwona Swiderska, Peter Pohl, Jochen S Hub, Sylvie Roke

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seonwoo LeeLaboratory for fundamental BioPhotonics (LBP), Institute of Bioengineering (IBI), and Institute of Materials Science (IMX), School of Engineering (STI), and Lausanne Centre for Ultrafast Science (LACUS), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH-1015, Switzerland.ORCID 0000-0003-1685-1988
Chetan S PoojariTheoretical Physics and Center for Biophysics, Saarland University, Saarbrücken 66123, Germany.ORCID 0000-0001-6575-221X
Anna MaznichenkoInstitute of Biophysics, Johannes Kepler University Linz, Gruberstraße 40, Linz 4020, Austria.
David RoeselLaboratory for fundamental BioPhotonics (LBP), Institute of Bioengineering (IBI), and Institute of Materials Science (IMX), School of Engineering (STI), and Lausanne Centre for Ultrafast Science (LACUS), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH-1015, Switzerland.ORCID 0000-0003-3894-4499
Iwona SwiderskaLaboratory for fundamental BioPhotonics (LBP), Institute of Bioengineering (IBI), and Institute of Materials Science (IMX), School of Engineering (STI), and Lausanne Centre for Ultrafast Science (LACUS), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH-1015, Switzerland.
Peter PohlInstitute of Biophysics, Johannes Kepler University Linz, Gruberstraße 40, Linz 4020, Austria.ORCID 0000-0002-1792-2314
Jochen S HubTheoretical Physics and Center for Biophysics, Saarland University, Saarbrücken 66123, Germany.ORCID 0000-0001-7716-1767
Sylvie RokeLaboratory for fundamental BioPhotonics (LBP), Institute of Bioengineering (IBI), and Institute of Materials Science (IMX), School of Engineering (STI), and Lausanne Centre for Ultrafast Science (LACUS), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH-1015, Switzerland.ORCID 0000-0002-6062-7871

Funding

European Research Council
6 · The paper itself

Abstract

Proton translocation through lipid membranes is a fundamental process in the field of biology. Several theoretical models have been developed and presented over the years to explain the phenomenon, yet the exact mechanism is still not well understood. Here, we show that proton translocation is directly related to membrane potential fluctuations. Using high-throughput wide-field second harmonic (SH) microscopy, we report apparently universal transmembrane potential fluctuations in lipid membrane systems. Molecular simulations and free energy calculations suggest that H

Indexed as

Lipid BilayersProtonsWaterMolecular Dynamics SimulationLipid BilayersProtonsWater

Identifiers

PMID38991220
PMCPMC11273352

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.