Evidence map›Paper›PMID 38991195›Full record

ArticleNeurology2024

Clinical Reasoning: A 17-Year-Old Adolescent Boy With New Altered Mental Status in the Pediatric Intensive Care Unit.

Robert T Ohman, Christie Atchison, Namrata D Patel, Elizabeth Y Killien

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert T OhmanFrom the Division of Pediatric Critical Care Medicine (R.T.O., E.Y.K.), Department of Pediatrics, University of Washington, Seattle; Texas Children's Hospital (C.A.), Houston; and Department of Neurology (N.D.P.), Medical College of Wisconsin, Children's Hospital Wisconsin-Milwaukee.
Christie AtchisonFrom the Division of Pediatric Critical Care Medicine (R.T.O., E.Y.K.), Department of Pediatrics, University of Washington, Seattle; Texas Children's Hospital (C.A.), Houston; and Department of Neurology (N.D.P.), Medical College of Wisconsin, Children's Hospital Wisconsin-Milwaukee.
Namrata D PatelFrom the Division of Pediatric Critical Care Medicine (R.T.O., E.Y.K.), Department of Pediatrics, University of Washington, Seattle; Texas Children's Hospital (C.A.), Houston; and Department of Neurology (N.D.P.), Medical College of Wisconsin, Children's Hospital Wisconsin-Milwaukee.
Elizabeth Y KillienFrom the Division of Pediatric Critical Care Medicine (R.T.O., E.Y.K.), Department of Pediatrics, University of Washington, Seattle; Texas Children's Hospital (C.A.), Houston; and Department of Neurology (N.D.P.), Medical College of Wisconsin, Children's Hospital Wisconsin-Milwaukee.

Funding

Clinical factors associated with long-term recovery following pediatric critical illness and injuryK23HD100566 · NICHD · UNIVERSITY OF WASHINGTON · PI KILLIEN, ELIZABETH Y · 2021 to 2025
$792k
NICHD NIH HHS K23 HD100566
6 · The paper itself

Abstract

We present the case of a 17-year-old adolescent boy admitted to the Pediatric Intensive Care Unit with an extensive necrotizing soft tissue infection who subsequently developed altered mental status and autonomic instability. Altered mental status is a common occurrence in critically ill children with a broad differential of etiologies. After ruling out organic causes of encephalopathy, management is typically focused on avoiding deliriogenic agents, including benzodiazepines. Dopamine antagonist medications may also be administered adjunctively to manage agitation or delirium that is refractory to other measures. We review the workup and differential diagnosis for altered mentation in critically ill children and discuss the current understanding of a rare etiology of altered mental status in the pediatric population.

Indexed as

Intensive Care Units, PediatricAdolescentClinical ReasoningDiagnosis, DifferentialHumansMale

Identifiers

PMID38991195
PMCPMC11247388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.