Evidence map›Paper›PMID 38991119›Full record

ArticleBlood advances2024

In utero hematopoietic stem cell transplantation for Fanconi anemia.

Leah Swartzrock, Carla Dib, Morgane Denis, Hana Willner, Katie Ho, Ethan Haslett, Jian Han, Wenjing Pan, Miranda Byrne-Steele, Brittany Brown and 7 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07408583 (A Phase I/II, Non-Randomized Study of the Safety and Efficacy of In Utero Hematopoietic Stem Cell Transplantation for the Treatment of Fanconi Anemia in Affected Fetuses), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07408583 phase1 / phase2not yet recruitingnot on this mapstarted 2028, after this paper: background citation

A Phase I/II, Non-Randomized Study of the Safety and Efficacy of In Utero Hematopoietic Stem Cell Transplantation for the Treatment of Fanconi Anemia in Affected Fetuses

TypeinterventionalSponsorAgnieszka CzechowiczRan2028 to 2033Enrolled12ConditionsFanconi Anemia, Anemia, Hypoplastic, Congenital, Congenital Bone Marrow Failure Syndromes, Bone Marrow Failure DisordersArmsIUHSCT for FA-affected fetuses
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Leah SwartzrockDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0003-0584-0896
Carla DibDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-7242-8327
Morgane DenisDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0002-9485-0131
Hana WillnerDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0009-0005-0003-6139
Katie HoDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Ethan HaslettDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Jian HaniRepertoire Inc, Huntsville, AL.
Wenjing PaniRepertoire Inc, Huntsville, AL.
Miranda Byrne-SteeleiRepertoire Inc, Huntsville, AL.
Brittany BrowniRepertoire Inc, Huntsville, AL.
Mark R KrampfDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Anna GirsenDivision of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA.
Yair J BlumenfeldDivision of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA.
Yasser Y El-SayedDivision of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA.
Maria G RoncaroloDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0003-1636-1495
Tippi C MacKenzieDivision of Pediatric Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.ORCID 0000-0001-5232-809X
Agnieszka D CzechowiczDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0003-2909-2669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fanconi AnemiaHematopoietic Stem Cell TransplantationFemaleHumansPregnancy

Identifiers

PMID38991119
PMCPMC11399615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.