Evidence map›Paper›PMID 38990326›Full record

ArticleJournal of agricultural and food chemistry2024

Multianalytical Approach to Understand Polyphenol-Mal d 1 Interactions to Predict Their Impact on the Allergenic Potential of Apples.

Julia A H Kaeswurm, Birgit Claasen, Pia S Mayer, Maria Buchweitz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of agricultural and food chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia A H KaeswurmDepartment of Chemistry, University Hamburg, Institute of Food Chemistry, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Birgit ClaasenUniversity Stuttgart, Institute of Organic Chemistry, Pfaffenwaldring 55, 70569 Stuttgart, Germany.
Pia S MayerDepartment of Food Chemistry, University Stuttgart, Institute of Biochemistry and Technical Biochemistry, Allmandring 5b, 70569 Stuttgart, Germany.
Maria BuchweitzDepartment of Chemistry, University Hamburg, Institute of Food Chemistry, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.ORCID 0000-0002-0107-3231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interactions between phenolic compounds and the allergen Mal d 1 are discussed to be the reason for better tolerance of apple cultivars, which are rich in polyphenols. Because Mal d 1 is susceptible to proteolytic digestion and allergenic symptoms are usually restricted to the mouth and throat area, the release of native Mal d 1 during the oral phase is of particular interest. Therefore, we studied the release of Mal d 1 under different in vitro oral digestion conditions and revealed that only 6-15% of the total Mal d 1 present in apples is released. To investigate proposed polyphenol-Mal d 1 interactions, various analytical methods, e.g., isothermal titration calorimetry,

Indexed as

AllergensMalusPolyphenolsAntigens, PlantDigestionFruitHumansMagnetic Resonance SpectroscopyMass SpectrometryPlant ProteinsAllergensAntigens, PlantMALD1 protein, Malus domesticaPlant ProteinsPolyphenols1H−15N-HSQC NMRapple allergyin vitro oral digestionisothermal titration calorimetrymass spectrometrypolyphenol–protein interactionsrelease

Identifiers

PMID38990326
PMCPMC11273618

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.