ArticleInternational forum of allergy & rhinology2024
Chitosan-based crosslinking for controlled topical drug release in rhinosinusitis.
Do-Yeon Cho, Dong Jin Lim, Olivia J Kelly, Daniel Skinner, Shaoyan Zhang, Martin P Jones, Jessica Grayson, Bradford A Woodworth
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In one paragraphArticle in International forum of allergy & rhinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
8 authors.
Do-Yeon ChoDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-5173-8959 Dong Jin LimDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Olivia J KellyNorthwestern University, Evanston, Illinois, USA.
Daniel SkinnerDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Shaoyan ZhangDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Martin P JonesDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jessica GraysonDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-2131-8005 Bradford A WoodworthDepartment of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-3292-9167 Funding
UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Steven Mark Rowe · 2007 to 2026
$23.0MIvacaftor for Acquired CFTR Dysfunction in Chronic RhinosinusitisR01HL133006 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WOODWORTH, BRADFORD ALAN · 2016 to 2020
$1.7MDysbiosis of the Sinus Microbiota in Chronic RhinosinusitisK08AI146220 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHO, DO-YEON · 2019 to 2021
$467kImpact of mucin fermenting microbes on the virulence of Pseudomonas aeruginosa in chronic rhinosinusitisR21AI168894 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHO, DO-YEON · 2022 to 2023
$408kA Ginsenoside TMEM16A Potentiator for Cystic FibrosisR21AT012234 · NCCIH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WOODWORTH, BRADFORD ALAN · 2023 to 2024
$405kNCCIH NIH HHS R21 AT012234NHLBI NIH HHS R01 HL133006NIAID NIH HHS K08 AI146220NIAID NIH HHS R21 AI168894NIDDK NIH HHS P30 DK072482
6 · The paper itselfAbstract
key pointsChitosan is a promising drug delivery vector for therapeutics owing to its biocompatibility. Once crosslinked with chitosan, prolonged drug release was noted regardless of hydrophilicity. Hydrophilic drugs may require different strategies to obtain a sustained release profile.
Indexed as
ChitosanDelayed-Action PreparationsRhinitisSinusitisAdministration, TopicalAnimalsCross-Linking ReagentsDrug Delivery SystemsDrug LiberationHumansRhinosinusitisChitosanCross-Linking ReagentsDelayed-Action Preparationschitosanciprofloxacinrhinosinusitistopical drug releasetopical steroid
Identifiers
PMID38990106
PMCPMC11530306
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