Evidence map›Paper›PMID 38989495›Full record

ReviewJournal of conservative dentistry and endodontics2024

Matrix metalloproteinase inhibitors in restorative dentistry.

I Perarivalan, Janani Karunakaran, Nathashri Anbalagan, S Harishma, Vishnu Prasad

Abstract readReview
In one paragraph

Review in Journal of conservative dentistry and endodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I PerarivalanDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
Janani KarunakaranDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
Nathashri AnbalaganDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
S HarishmaDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
Vishnu PrasadDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) have been identified as agents that disintegrate the collagen structures of dental hybrid layers, resulting in reduced restorative bond strength. Multiple MMP inhibitors (MMPIs) are known to counteract this degenerative mechanism, thereby preserving bond strength and promoting the longevity of resin-based restorations. Additionally, literature suggests that certain MMPI materials possess antimicrobial/anticariogenic properties, potentially reducing the risk of secondary caries development. Therefore, this review article aims to narrate on the integration of matrix metalloproteinase inhibitors into adhesive systems and their impact on bond strength.

Indexed as

matrix metalloproteinase inhibitorsMatrix metalloproteinase inhibitors and bond strengthmatrix metalloproteinases

Identifiers

PMID38989495
PMCPMC11232771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.